Dr Yen Ying Lim
NHMRC
Australia
Genetic mechanisms that moderate effects of Aß accumulation in preclinical Alzheimer's disease
NHMRC
409,460
01/01/16
4.0
Alzheimer's disease & other dementias
alzheimer disease | amyloid | apolipoprotein e | biomarkers | cognition
Alzheimers disease (AD) is the most common form of dementia, and the number of people living with it will triple by 2050. There is currently no cure for AD, and the only means of slow the growing epidemic is to delay onset. We propose to understand the complex interplay between genetic, cognitive, neuroimaging and biological markers of AD in order to better understand the disease process, and in turn identify high-risk individuals for clinical trials and uncover disease-modifying strategies.