Name of Fellow


Dr Adam Walker

Institution


Funder


NHMRC

Contact information of fellow


Country


Australia

Title of project/programme


Investigating mechanisms of dementia and motor neuron disease

Source of funding information


NHMRC

Total sum awarded (Euro)


€ 214,890

Start date of award


01/01/12

Total duration of award in years


6.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


amyotrophic lateral sclerosis | dementia | protein aggregation | motor neuron disease (mnd) | cell biology

Research Abstract


Dementia and motor neuron disease (MND) are both neurodegenerative diseases which have devastating impacts on patients and their families. My research investigates the biochemical mechanisms involved in these diseases. Pathology in the nervous system of dementia and MND patients contains a protein called ‘TDP-43’, but it remains unknown how this causes disease. This project will therefore explore the effects of TDP-43 malfunction, which will provide insight into potential therapeutic strategies.

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