Name of Fellow


Dr Angela D'Rozario

Institution


Funder


NHMRC

Contact information of fellow


Country


Australia

Title of project/programme


Sleep, plasticity and neurodegeneration: Targeting sleep to improve cognition in Mild Cognitive Impairment (MCI)

Source of funding information


NHMRC

Total sum awarded (Euro)


€ 350,153

Start date of award


01/01/16

Total duration of award in years


5.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


sleep | dementia-related decline in memory | sleep disturbance | neurophysiology | neuroimaging

Research Abstract


Older individuals with mild cognitive impairment commonly experience disturbed sleep and about 50% will convert to dementia. It is unclear whether sleep disturbance mediates cognitive decline and progression to dementia. Optimising sleep presents a novel strategy to slow disease progression. This new research program explores links between sleep and dementia to identify new biomarkers of disease progression and new targeted therapeutic approaches to improve quality of life for older Australians.

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