Prof Sharon Naismith
NHMRC
Australia
Modifiable risks and interventions for older people 'at risk' of dementia
NHMRC
288,137
01/01/11
6.0
Alzheimer's disease & other dementias
cognitive decline | neural plasticity | depression | neurodegeneration | dementia
This research proposal will explore the modifiable risk factors for cognitive decline (ie. changes in memory and thinking functions) in older people. It will examine the pertinence of critical contributors to glial-neuronal networks including depression, cardiovascular disease, sleep-wake systems, mental and physical exercise, inflammatory processes and diet, as well as test interventions that target these risk factors. It will use sophisticated brain scanning methods to examine which factors promote neuroplasticity.