Name of Fellow


Prof Malcolm Horne

Institution


Funder


NHMRC

Contact information of fellow


Country


Australia

Title of project/programme


Practitoner Fellowship

Source of funding information


NHMRC

Total sum awarded (Euro)


€ 369,419

Start date of award


01/01/12

Total duration of award in years


5.0

The project/programme is most relevant to:


Motor neurone diseases

Keywords


parkinson disease | alpha-synuclein | motor neuron disease (mnd) | dyskinesia | biomaterials

Research Abstract


Trials of numerous agents to slow the progression of Parkinsons disease have provided ambiguous or negative results despite having good preliminary evidence for their efficacy. The most likely reason is that many nerve cells are already destroyed by the time of diagnosis. Thus effective therapies may be most (and possible only) effective when administered in the presymptomatic stages of disease. This proposal is directed at developing method to detect early presymptomatic Parkinsons disease.

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