Principal Investigators


Prof. dr. Jan Veldink

Institution


UMCU

Contact information of lead PI


Country


Netherlands

Title of project or programme


Project Beyond MinE-NL

Source of funding information


Stichting ALS

Total sum awarded (Euro)


€ 1,508,159

Start date of award


01/01/2015

Total duration of award in years


3.0

The project/programme is most relevant to:


Motor neurone diseases

Keywords


Research Abstract


As the cause of sporadic ALS has not been discovered by researchers up to now, Project MinE has been set up – the largest genetic ALS research initiative to date that should overcome the power problems of previous genetic studies.
Project MinE researchers aim to analyse the genomes of 15,000 ALS patients and 7,500 control subjects worldwide with whole genome sequencing. Sequencing implies reading all genes of the genome. This generates more than 6 petabyte of data. This amount of data is almost unprecedented in medical research. Obviously, this amount of data needs the best and largest facilities for storing and analysing and these are now being arranged
To enable this important and innovative process of untangling the whole genome sequencing data of 22,500 DNA samples, the Netherlands ALS Foundation has approved a grant application of the ALS Centre Netherlands for the costs of data storage and analyses for the Project MinE consortium (called ‘Beyond Project MinE NL’)

Lay Summary


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