Name of Resource

    Oxford Parkinson Disease Centre (University of Oxford)

    Name of Principal Investigator - Title

    Prof

    Name of Principal Investigator - First name

    Richard

    Name of Principal Investigator - Last name

    Wade-Martins

    Address of institution -Institution

    University of Oxford

    Address of institution - Street address

    South Parks Road

    Address of institution - City

    Oxford

    Address of institution - Postcode

    OX1 3QX

    Country

    United Kingdom

    Website
    Contact email
    Summary

    BAC trangsenic mouse and rat lines carrying wild-type or mutant variants of SNCA and LRRK2; human iPSC lines carrying mutations in SNCA, LRRK2, GBA and sporadic PD, plus controls

    Q1a. Please indicate below if your cohort includes or expects to include, incidence of the following conditions? (1)

    Parkinson's disease & PD-related disorders

    Q1b. Does your resource hold

    Animals| Induced Pluripotent Stem Cells (iPSC)

    Q2a. Does the resource act as a centre for access and distribution to external groups (who are not the Principal Investigators (PI) for the resource)?

    Yes

    Q2b. If Yes, what procedures and rules apply for access?

    Apply to PI or co-ordinator at resource|Access through collaboration with PI only| Access independent of collaboration with PI| Local/ regional access| National access| International access| Charge for retrieval

    Q3a. Does your resource develop experimental models (animal/cell) for external groups?

    No

    Q3b. If YES and your resource is related to an ANIMAL model, what types of models are provided?

    Q3c. If YES and your resource is related to a CELL model, what types of models are provided?

    Q4a. Is this activity supported as:

    Not applicable

    Q4b. Do you deposit what you supply in any kind of central repository?

    Disease

    PD | PD| PD

    Species

    Mouse| Mouse| Rat

    Available to external user

    Yes through JAX| Yes Through Jax| Yes through www.rrc.us/

    Full phenotypic character

    Published PMID24082145| Published PMID 24121116| Published PMID 26744332

    Please indicate the phenotypes

    Published| Published| Published

    List of genotypes or other subtypes

    SNCA-OVX| SNCA-A30P| LRRK2-WT, LRRK2-G2019S, LRRK2-R1441C

    Q5b. Cognitive function, No of models

    Q5b. Cognitive function, Available to external users

    Q5b. Cognitive function, Full phenotypic characterisation

    Q5b. Cognitive function, Nature of phenotype

    Q5b. Motor function, No of models

    Q5b. Motor function, Available to external users

    Q5b. Motor function, Full phenotypic characterisation

    Q5b. Motor function, Nature of phenotype

    Q5b. Physiological function, no of models

    Q5b. Physiological function, Available to external users

    Q5b. Physiological function, Full phenotypic characterisation

    Q5b. Physiological function, Nature of phenotype

    Q5b. Other function (please specify), no of models

    Please specify other function

    Q5b. Other function (please specify), Available to external users

    Q5b. Other function (please specify), Full phenotypic characterisation

    Q5b. Other function (please specify), Nature of phenotype

    Q6. Please indicate if your resource is already linked into European or international consortia or networks?

    Q7a. Is maintenance of this resource dependent on continued funding?

    Q7b. If yes, when does the current funding period end?

    Q7c. What is the expected lifespan of the resource (in years)?

    Q7d. Are there other plans affecting future use that it may be useful to know?

Types: Experimental Models
Member States: United Kingdom
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

Export as PDF