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The Vallecas Project is developed in the Research Unit of the Alzheimer’s Center of the Reina Sofía Foundation by researchers of the CIEN Foundation. Its main objective is to determine a probabilistic algorithm for the identification of individuals at risk of dementia type Alzheimer’s disease (AD) in the course of a few years. This algorithm will be based on the combination of sociodemographic, clinical, neurological, neuropsychological, biological (from blood determinations) and neuroimaging (various 3 Tesla magnetic resonance modalities).
The recruitment phase of the Vallecas Project participants was extended from October 2011 to December 2013. Finally, a total of 1,213 volunteers aged between 70 and 85 and of both sexes were initially evaluated. Once included in the study, it is monitored annually for 5 years in order to assess the evolutionary profile of all participants, specifically identifying those who develop cognitive impairment and / or dementia. The cohort is being followed up annually for 4 years after the baseline.
Types Neurodegenerative disease-specific cohort
Participant Types At-risk diagnosis
Countries Spain
Genders Male and Female
Sample sizes 0 to 4,999
Ages 60 to 100
Brain related measures Behaviour|Cognitive function|Mental health|Neurological
Funtional rating Individual physiological|Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Hearing and Vision
Biological samples Blood
Genotyping Gene screening
Brain imaging Magnetic resonance imaging (MRI)
Brain banking Consent for brain donation
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Informal support|Marital status|Occupation and employment
Health service utilisation Formal health and social care service utilisation including private care
Institute names Alzheimer center Queen Sofia Foundation (CIEN Foundation)
Current Sample Sizes 0 to 4,999
age at recruitment 70-85
last updated 20180409
recruitment period 2011-2013
estimated current sample size number value 1169
cohort acronym VP-EDAD
start date 2011
pi Miguel Medina
website http://www.fundacioncien.es/proyectos-de-investigacion/proyecto-vallecas
contact details Alzheimer center Queen Sofia Foundation (CIEN Foundation)
C / Valderrebollo, 5
Centro Alzheimer Reina Sofía Foundation
Spain
abstract The Vallecas Project’s main objective is to determine a probabilistic algorithm for the identification of individuals at risk of dementia type Alzheimer’s disease (AD). VP-EDAD has recruited 1,213 participants.
funders Queen Sofia Foundation; ISCIII
contact email [email protected]; [email protected]
contact phone number
estimated current sample size 1169
sample sizes 1213