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AiBL
The Australian Imaging, Biomarkers & Lifestyle Flagship Study of Ageing
https://aibl.csiro.au
[email protected]
Only through the study
Australia
Yes
Apply to PI or co-ordinator at resource|Access Committee mechanism|Other access mechanism|International access|Access to industry|Access for pilot studies permitted|Applicant needs to provide separate external ethics approval|Resource has own ethics approval so usually no need for separate external ethics approval
Data made publicly available after a specified time point
Yes
Living donors: blood|Living donors: blood derivatives|Living donors: cerebro-spinal fluid|Living donors: cerebro-spinal fluid|Post-mortem donors: spinal cord
Primary samples: Supplied fresh|Primary Samples: Stabilised samples (frozen or fixed)|Secondary samples:(derivatives of primary samples)|Secondary samples: plasma|Secondary samples: DNA|Secondary samples: RNA|Secondary samples: protein extracts
Yes
Yes, for all the cohort
Longitudinal observational study of the natural history of AD
189
Lim YY. Sensitivity of composite scores to amyloid burden in preclinical Alzheimer’s disease: Introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score. 2016|Gupta VB. Plasma apolipoprotein J as a potential biomarker for Alzheimer’s disease: Australian Imaging Biomarkers and Lifestyle Study of ageing. 2016|Lim YY. Performance on the Cogstate Brief Battery is related to amyloid levels and hippocampal volume in very mild dementia. 2016
Refer to AiBL website: https://aibl.csiro.au
1,001-5,000
501-1,000
See: Ellis KA et al. Enabling a multidisciplinary approach to the study of ageing and Alzheimer’s disease: an update from the Australian Imaging Biomarkers and Lifestyle (AIBL) study. Int Rev Psychiatry. 2013; 25:699-710
No
No
Prospective cohort|Genome wide association study (GWAS)|Age|Sex
Co-morbidities|Cognitive function|Physical ability
No
Data collection ongoing
Yes – funding applied for
Data summarised in database
Data summarised in database
Database on spreadsheet (e.g. excel)
No
No
Data is web-based
The Australian Imaging, Biomarkers & Lifestyle Flagship Study of Ageing
Alzheimer’s disease and other dementias|Neurodegenerative disease in general
Case Control Studies
Australia
Alzheimer’s disease & other dementias|Neurodegenerative disease in general
2016