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TgF344-AD (University College Cork)
Ireland
TgF344-AD (University College Cork)
Rat model of AD (TgF344-AD), which expresses the mutant human transgenes: amyloid precursor protein (APPsw) and presenilin 1 (PS1ΔE9).
Alzheimer’s disease & other dementias
Animals
Yes
Apply to PI or co-ordinator at resource| Access through collaboration with PI only| National access| International Access| Applicant needs to provide separate external ethics approval| Other requirements exist
No
Wild type| Genetically Modified
No
AD
Rat
Yes, but with specifications
F344 rat expressing PS1 (delta E9) and APPswe mutations
See Cohen et al., (2013). J. Neurosci. 33(15), 6245
EBiSC| StemBANCC
Yes
2017
Indefinite, if storage funded
StemBANCC sustaininability award application
Experimental Models
Ireland
2016