Danish 1905 Cohort Study

The overall goal was to establish a genetic-epidemiological database to shed light on the aging process among the extremely old, focusing on physical and cognitive functioning. In the first wave 2,262 Danes born in 1905 participated in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness.

The first wave took place in 1998 and participants were followed-up in 2000 and 2003. In 2005 all the surviving birth cohort members were invited to participate irrespective of previous participation:

• Wave 1: 2262 participants (1653 with biological sample)
• Wave 2: 1086 participants
• Wave 3: 437 participants
• Wave 4: 256 participants

Last update – 30/01/2017

Types General population-based cohort
Participant Types No diagnosis
Countries Denmark
Genders Male and Female
Sample sizes 0 to 4,999
Ages 60 to 100
Brain related measures Cognitive function|Mental health|Neurological
Funtional rating Individual physiological|Individual psychological
Anthropometric Height|Waist circumference|Weight
Physical Cardiovascular|Hearing and Vision|Musculoskeletal|Reproductive|Respiratory
Biological samples Blood|Other
Genotyping Gene screening
Brain imaging
Brain banking
Lifestyle Alcohol|Physical activity|Smoking
Socio-economic Education|Family circumstances|Housing and accommodation|Informal support|Marital status|Occupation and employment|Unpaid care
Health service utilisation Formal health and social care service utilisation including private care
Institute names University of Southern Denmark
Current Sample Sizes 0 to 4,999

age at recruitment 92-100
last updated
recruitment period 1998-2005
estimated current sample size number value 0
cohort acronym DCS-1905
start date 1998-2005
pi Professor Kaare Christensen and Professor Bernard Jeune
website http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/3960
contact details University of Southern Denmark
Epidemiology, Biostatistics and Biodemography,
Odense,
DK
abstract  DCS began in 1905 and focused on physical and cognitive functioning in the extremely old (92-100). 2,262 Danes were selected in 1998 through population-based registers.
funders  Danish National Research Foundation
United States Department of Health and Human Services
National Institutes of Health
National Institute on Aging (NIA)
contact email PI Email: [email protected] PI Email: [email protected]
contact phone number +45 65503049
estimated current sample size 0 to 4,999
sample sizes 2262