British Regional Heart Study

The British Regional Heart Study (BRHS) is a prospective study in middle-aged men drawn from general practices in 24 British towns, 7,735 men were recruited in 1978-1980. It was set up to determine the factors responsible for the considerable variation in coronary heart disease, hypertension and stroke in Great Britain. It also seeks to determine the causes of these conditions in order to provide a rational basis for recommendations towards their prevention.

Following the collection of baseline date in 1978-80 the cohort has been followed up through the participants, two-yearly GP Record Reviews, and the Office of Population and Census Surveys. Participants have been re-contacted through questionnaires or assessment in 1983-85, 1992, 1996, 1998-2000, 2003, 2005, 2007 and 2010-2012, 2014, 2015, 2016.

Last update – 21/02/2017

Types General population-based cohort
Participant Types No diagnosis
Countries United Kingdom
Genders Male
Sample sizes 5,000 to 9,999
Ages 40 to 59|60 to 100
Brain related measures Cognitive function|Mental health|Neurological
Funtional rating Individual physiological|Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Hearing and Vision|Musculoskeletal|Respiratory
Biological samples Blood|Urine
Genotyping
Brain imaging
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Housing and accommodation|Income and finances|Informal support|Marital status|Occupation and employment
Health service utilisation
Institute names University College, London
Current Sample Sizes 5,000 to 9,999

age at recruitment 40-59
last updated
recruitment period 1978-80
estimated current sample size number value 27172
cohort acronym BRHS
start date 1978-80
pi Professor Peter Whincup and Professor Goya Wannamethee
website http://www.ucl.ac.uk/pcph/research-groups-themes/brhs-pub
contact details British Regional Heart Study (BRHS)
Department of Primary Care & Population Health
Institute of Epidemiology and Health Care
UCL Faculty of Population Health Sciences
UCL Medical School
Royal Free Campus
Rowland Hill Street,
London NW3 2PF UK
abstract  BRHS is a population study set up to determine the factors responsible for the considerable variation in coronary heart disease, hypertension and stroke in Great Britain. Since 1978 7,735 middle aged men have been recruited .
funders  British Heart Foundation
contact email [email protected]
contact phone number ‘+44 (0) 207 830 2335 U20
estimated current sample size 0 to 4,999
sample sizes 7735