Lausanne cohort 65+

The Lc65+ project is a longitudinal population-based study focusing on the development of frailty after the age of 65. The main methods in the Lc65+ study are:

ﾕ long term observation of subjects, beginning at 65 to 70 years, an age when frailty is still unusual, in order to study its initiation and development;
ﾕ prospective data collection on a large range of health dimensions, including psycho-social characteristics, in order to investigate the temporal sequence linking frailty, its risk factors, modulators, and outcomes:
ﾕ a population approach considering frailty as a central parameter of health in ageing populations that is useful not only for surveillance, but also for the evaluation of preventive interventions.

Follow-up is based on a yearly questionnaire sent by mail to the participant’s home. In addition, subjects are invited to the study center every three years for an interview and examination similar to those performed at baseline. The follow-up is unlimited in time and is not interrupted in the case of nursing home admission.

Last Update 21/09/2017

Types General population-based cohort
Participant Types No diagnosis
Countries Switzerland
Genders Male and Female
Sample sizes 0 to 4,999
Ages 60 to 100
Brain related measures Cognitive function
Funtional rating Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Hearing and Vision
Biological samples
Genotyping
Brain imaging
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Family circumstances|Housing and accommodation|Income and finances|Informal support|Occupation and employment
Health service utilisation Formal health and social care service utilisation including private care
Institute names Lausanne University Institute of Social and Preventive Medicine (IUMSP)
Current Sample Sizes 0 to 4,999

age at recruitment 65-70
last updated
recruitment period 2004,2009 and 2014
estimated current sample size number value 3500
cohort acronym Lc65+
start date 2004,2009 and 2014
pi Prof. Brigitte Santos-Eggimann
website http://www.lc65plus.ch/en/lc65_home
contact details Lausanne cohorte Lc65+
CHUV – Institute of Social and Preventive Medicine
Health Services Unit
Biopole 2, Route de la Corniche 10, SA-V
CH-1010 Lausanne
abstract  The Lc65+ project is a longitudinal population-based study focusing on the development of frailty after the age of 65. Recruitment began in 2004, 4731 participants were recruited.
funders  City of Lausanne
Public Health Department of the Vaud canton, Lausanne
Lausanne University Hospital (CHUV)
Institute of Social and Preventive Medicine (IUMSP), CHUV, Lausanne
Community Medicine and Health Department (DUMSC), CHUV, Lausanne
Geriatrics and Geriatric Rehabilitation Service, CHUV, Lausanne
Ambulatory Medical Policlinic (PMU), Lausanne
Loterie Romande
Faculty of Biology and Medicine, University of Lausanne
Swiss National Foundation for Scientific Research (SNF)
contact email Email: [email protected] PI Email: [email protected]
contact phone number Tel: +41 21 314 97 70
estimated current sample size 0 to 4,999
sample sizes 4731