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For the Esprit study, 1863 non-institutionalized persons aged 65 years and over were randomly recruited in 1999 from the Montpellier district electoral rolls, and re-examined 6-times at 2-3 yearly intervals. Objectives:
1) To determine current and lifetime prevalence as well as incidence of psychiatric disorder in the elderly;
2) to determine the risk factors for these disorders, their relative weight and interactions;
3) to study clinical heterogeneity;
4) to estimate the probability of transition towards a subsyndromic state or a given pathology;
5) to elaborate predictive etiological models.
Types General population-based cohort
Participant Types No diagnosis
Countries France
Genders Male and Female
Sample sizes 0 to 4,999
Ages 60 to 100
Brain related measures
Funtional rating Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Hearing and Vision|Reproductive|Respiratory
Biological samples Blood|Other|Saliva
Genotyping Gene screening
Brain imaging Magnetic resonance imaging (MRI)|Magnetoencephalography (MEG)
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Housing and accommodation|Income and finances|Marital status|Occupation and employment
Health service utilisation Formal health and social care service utilisation including private care
Institute names Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm
Current Sample Sizes 0 to 4,999
age at recruitment 65 and over
last updated
recruitment period 1999-2001
estimated current sample size number value 926
cohort acronym ESPRIT
start date 1999-2001
pi Marie-Laure Ancelin and Karen Ritchie
website https://hal.archives-ouvertes.fr/inserm-00138456/
contact details Inserm U1061, Montpellier, France
abstract For the Esprit study, 1863 non-institutionalized persons aged 65 years and over were randomly recruited in 1999 from the Montpellier district electoral rolls. ESPIRIT recruited 1863 participants.
funders Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm
contact email PI email: [email protected]; PI email: [email protected]
contact phone number Tel: +33 4 99 61 45 62
estimated current sample size 0 to 4,999
sample sizes 1863
