The Maastricht Study

The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes, its classic complications (cardiovascular disease, nephropathy, neuropathy and retinopathy), and its emerging comorbidities, including cognitive decline, depression, and gastrointestinal, respiratory and musculoskeletal diseases. The study uses advanced state-of-the-art imaging techniques and extensive biobanking to determine health status in a population-based cohort of 10,000 individuals that is enriched with type 2 diabetes participants. The Maastricht Study is expected to become one of the most extensive phenotyping studies in both the general population and type 2 diabetes participants worldwide.

The Maastricht Study allows researchers access to data to encourage publications of high quality papers and presentations. External researchers (those without an MUMC or UM affiliation) can only submit a research proposal in cooperation with a member of the Maastricht Study Management Team and/or Maastricht Study Participating researchers.

Types General population-based cohort
Participant Types Condition diagnosed
Countries Netherlands
Genders Male and Female
Sample sizes 10,000 to 19,999
Ages 40 to 59|60 to 100
Brain related measures
Funtional rating Individual physiological|Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Musculoskeletal|Respiratory
Biological samples Blood|Microbiome|Urine
Genotyping Gene screening
Brain imaging Magnetic resonance imaging (MRI)
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Income and finances|Informal support|Marital status|Occupation and employment
Health service utilisation Formal health and social care service utilisation including private care
Institute names Maastricht University
Current Sample Sizes 10,000 to 19,999

age at recruitment 40-75
last updated
recruitment period
estimated current sample size number value 7,500
cohort acronym
start date
pi Miranda Schram, Coen Stehouwer
website https://www.demaastrichtstudie.nl/research
contact details Maastricht University Medical Center
Research Center Maastricht Study
Randwycksingel 35
6229 EG Maastricht
abstract  The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes, its classic complications and its emerging comorbidities, including cognitive decline. The Maastricht Study has recruited 7,500 participants.
funders  European Regional Development Fund, Stichting De Weijerhorst (Maastricht, the Netherlands), the Pearl String Initiative Diabetes (Amsterdam, the Netherlands), the Cardiovascular Center (CVC, Maastricht, the Netherlands), School for Mental Health and Neuroscience (MHeNS), Maastricht, The Netherlands), Cardiovascular Research Institute Maastricht (CARIM, Maastricht, the Netherlands), School for Public Health and Primary Care (CAPHRI, Maastricht, the Netherlands), School for Nutrition, Toxicology and Metabolism (NUTRIM, Maastricht, the Netherlands), Stichting Annadal (Maastricht, the Netherlands), Health Foundation Limburg (Maastricht, the Netherlands) and by unrestricted grants from Janssen-Cileg B.V. (Tilburg, the Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, the Netherlands) and Sanofi-Aventis Netherlands B.V. (Gouda, the Netherlands).
contact email [email protected]; [email protected]
contact phone number Tel: +31 (0) 43 – 387 66 00
estimated current sample size 5,000 to 9,999
sample sizes 10,000