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A family-based cohort study that is embedded in the Genetic Research in Isolated Populations (GRIP) program in the South West of the Netherlands. The aim of this program was to identify genetic risk factors in the development of complex disorders. For the ERF study, 22 families that had at least five children baptized in the community church between 1850-1900 were identified with the help of genealogical records. All living descendants of these couples and their spouses were invited to take part in the study. Data collection started in June 2002 and was finished in February 2005 (n=2065).
Types General population-based cohort
Participant Types Condition diagnosed
Countries Netherlands
Genders Male and Female
Sample sizes 0 to 4,999
Ages 10 to 19|20 to 39|40 to 59|60 to 100
Brain related measures
Funtional rating Individual physiological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Hearing and Vision|Musculoskeletal|Reproductive|Respiratory
Biological samples Blood
Genotyping Gene screening
Brain imaging Electroencephalogram (EEG)|Magnetic resonance imaging (MRI)
Brain banking
Lifestyle Alcohol|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Income and finances|Informal support|Martial status|Occupation and employment|Unpaid care
Health service utilisation
Institute names Erasmus Medical Center
Current Sample Sizes 0 to 4,999
age at recruitment 17-80
last updated
recruitment period Jun-02
estimated current sample size number value 2,065
cohort acronym ERF
start date Jun-02
pi Dr. Cornelia van Duijn and Dr Aaron Issacs
website http://www.gefos.org/?q=content/erasmus-rucphen-family-study-2
contact details Department of Epidemiology
Erasmus Medical Center
PO Box 2040
3000 CA Rotterdam
the Netherlands
abstract The aim of the Erasmus Rucphen Family (ERF) study was to identify genetic risk factors in the development of complex disorders. Data collection started in June 2002 and was finished in February 2005 (n=2065).
funders European Commission, European Communitys Seventh Framework Programme
contact email [email protected]
contact phone number ‘+31 (0) 10 70 43394 or +31 (0) 10 70 38194
estimated current sample size 0 to 4,999
sample sizes 2,097