BRAINS Unit, Lund University

Name of resource
BRAINS Unit, Lund University
Name of Principal Investigator

Title Professor
First name Deniz
Last name Kirik

Address of institution where award is held

Institution Lund University
Street Address BMC D11
City Lund
Postcode 22184

Country

  • Sweden

    • Website
    http://www.med.lu.se/expmed/brains
    Contact email
    [email protected]
    Summary
    We run a small vector production facility that makes high quality AAV vectors that we use to develop animal models of PD and HD.
    1a. The resource holds animal models relevant to the study of the following neurodegenerative diseases

  • Parkinson’s disease
  • Huntington’s disease

    • 1b. The resource holds:

  • Animals
  • Frozen embryos
  • Genetic material (DNA, RNA, vectors etc)

    • 2a. The resource acts as a centre for access and distribution to external groups (who are not the PIs of the resource)

    2b. Procedures and rules for access

  • Access through collaboration with PI only

    • 3a. Does the resource develop animal models for external groups
    1
    3b. Types of models provided

    4a This activity is supported as:

  • Independent of collaboration

    • 4b. The supplied material deposited in a central repository
    1
    5a Disease models available

    Disease Species Available to external user (Y/N) Full phenotypic character (Y/N or partial) Phenotypes Genotypes or other subtypes
    PD rat, mouse, primate partial partial DA cell loss alpha-synuclein
    HD rat, mouse partial partial metabolic dysfunction huntingtin

    5b. Other models/phenotypes available through the resource relevant to neurodegenerative conditions

    No. of models Available to external users Full phenotypic characterisation available (Y/N or partial) Nature of phenotype
    1 partial partial behavior and pathology
    2 partial partial behavior and pathology

    6. European or international consortia or networks to which the resource is linked

    Jackson Laboratories, USAInternational mouse knockout consortium
    Neugene
    MEFOPA
    Neurasyn

    7a. Maintenance of the resource is dependent on continued funding
    2
    7b. End date of current funding period
    2012-13
    7c. Expected lifespan of the resource (in years)
    2

    BRAINS Unit, Lund University

    Experimental Models
    Sweden
    Huntington’s disease|Parkinson’s disease & PD-related disorders
    2011

     

     

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