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Signaling Pathways Regulating Neuronal Survival Investments > €500k United States of America Huntington’s disease 2016    

Biological and Pathological Interactions between Tau and LRRK2 Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

The Biology of Neuroserpin Investments > €500k United States of America Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders 2016    

GGGGCC hexanucleotide repeat expansions in neurodegenerative disease Investments > €500k United States of America Alzheimer’s disease & other dementias|Motor neurone diseases 2016    

Mechanisms Underlying Excitability Regulation of Motoneuron Types in ALS Investments > €500k United States of America Motor neurone diseases 2016    

RNA Processing Defects in SMA and Their Contribution to the Disease Phenotype Investments > €500k United States of America Spinal muscular atrophy (SMA) 2016    

Regulation of Mitochondrial Function and Motor Neuron Degeneration in SMA Investments > €500k United States of America Spinal muscular atrophy (SMA) 2016    

Smad Signaling in Skeletal Muscle as a Biomarker of Disease Progression in ALS Investments > €500k United States of America Motor neurone diseases 2016    

Exosomes and Neuroinflammation in Parkinsons Disease Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Study on hnRNPA1 Pathobiology in ALS Investments > €500k United States of America Motor neurone diseases 2016    

Functional dissection of therapeutic deep brain stimulation circuitry Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Early life brain inflammation and vulnerability to neurodegeneration in late life Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Role of Mitochondria-Targeted CYP2D6 in Chemical Toxicity Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Mitochondrial fission in Huntingtons Disease Investments > €500k United States of America Huntington’s disease 2016    

Mechanisms of synaptic dysfunction in Parkinsons and other synuclein-linked dise Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Effect of Unilateral and Bilateral STN Stimulation on Eye-Hand Coordination Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Silencing C9or72 with rAAV Mediated RNAi Investments > €500k United States of America Motor neurone diseases 2016    

Neuronal regulation of mitochondrial dynamics in models of Parkinsons disease. Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Single Molecule Studies of Protein Folding Mechanisms Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Predictors of progression to freezing of gait in Parkinsons disease Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Multiple Approaches to Abeta Vaccination in Animal Models Investments > €500k United States of America Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders 2016    

Protein Aggregation and Inflammasome Signaling in Manganese Neurotoxicity Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Unfolded Protein Response in Alpha-synucleinopathies Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Modeling the progression of SOD1-linked motor neuron disease Investments > €500k United States of America Motor neurone diseases 2016    

Muscle stem cells: New ALS growth factor therapy and disease model Investments > €500k United States of America Motor neurone diseases 2016    

Rhes-SUMO circuitry in Huntingtons Disease Pathogenesis Investments > €500k United States of America Huntington’s disease 2016    

A Drosophila model for studying mechanisms of Gauchers disease and synucleinopathies Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Pathophysiology of Transgenic Mouse Models of Huntingtons Disease Investments > €500k United States of America Huntington’s disease 2016    

Active zone loss cause dying back neuropathy in amyotrophic lateral sclerosis Investments > €500k United States of America Motor neurone diseases 2016    

Mechanisms of Neurodegeneration in ALS Investments > €500k United States of America Motor neurone diseases 2016    

POSTMORTEM VALIDATION OF BIOMARKERS FOR IMAGING PARKINSON DISEASE Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Role of MMP-9 in selective motor neuron degeneration in ALS Investments > €500k United States of America Motor neurone diseases 2016    

Functional Analysis of O-GlcNAc Modifications Using Synthetic Protein Chemistry Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Exploring the contribution of astrocytes to Huntington disease Investments > €500k United States of America Huntington’s disease 2016    

Investigating a2-chimaerin-dependent motor neuron protection in ALS Investments > €500k United States of America Motor neurone diseases 2016    

Regulation of cellular release of proteins in Parkinson neurodegeneration Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Mechanisms of Aggregated Alpha-Synuclein Induction and Progression Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Molecular mechanisms of Parkin-directed mitochondrial quality control Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

The role of a Synuclein transcript variants in neuronal pathology and function Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Klotho and Neurodegenerative Disease Investments > €500k United States of America Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders 2016    

Self-association and membrane binding of alpha-synuclein Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

A Software Platform for Sensor-based Movement Disorder Recognition Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

Glial huntingtin and neurodegeneration Investments > €500k United States of America Huntington’s disease 2016    

Role of Oligodendroglia in the Pathogenesis of ALS Investments > €500k United States of America Motor neurone diseases 2016    

The Regulation of Synaptic Connectivity and Homeostasis by Huntingtin Investments > €500k United States of America Huntington’s disease 2016    

Role of HLA/MHCII in Parkinsons Disease Pathogenesis Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Investments > €500k United States of America Motor neurone diseases 2016    

Matrix Metalloproteinases: Therapeutic Targets For Huntingtons Disease Investments > €500k United States of America Huntington’s disease 2016    

Systematic discovery and functional analysis of the PARKIN modified proteome Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016    

The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016