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European DNA bank to decipher the Alzheimer disease missing heritability Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

The preventive potential of nutrition on brain changes underlying deterioration of cognitive behaviour with ageing using advances neuro-imaging techniques Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Defining Genetic Polygenic and Environmental Risk for Alzheimer’s disease using multiple powerful cohorts,focussed Epigenetics and Stem cell metabolomics Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

The Maastricht Study Investments > €500k Netherlands Alzheimer’s disease & other dementias|Neurodegenerative disease in general 2016    

Biobank Alzheimer Center Limburg Cohort (BB-ACL) Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Evaluation of the impact of the AlzheimerNet programme: a Comparative Effectiveness Research on the transit from fragmented care to a collaborative dementia networks of multidisciplinary care Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Living arrangements for people with dementia (monitor woonvormen dementie) Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Dyskinesia induced by L-dopa in Parkinson’s disease: New mechanisms and molecular targets. Discinesia indotta dalla L-DOPA nella malattia di Parkinson: nuovi meccanismi e targets molecolari. Investments > €500k Italy Parkinson’s disease & PD-related disorders 2016    

Hereditary ataxias, an integrated study: genomic approach to the pathogenetic mechanisms by animal and cellular models. Atassie ereditarie, uno studio integrato: dall’approccio genomico ai meccanismi patogenetici mediante modelli animali e cellulari. Investments > €500k Italy Motor neurone diseases|Neurodegenerative disease in…

Neurodegeneration and Neuroprotection: the role you neuroglobin expression induced by estrogen hormones. Neurodegenerazione e Neuroprotezione: Ruole dell’espressione della neuroglobina indotta dagli ormoni estrogeni. Investments > €500k Italy Alzheimer’s disease & other dementias|Huntington’s disease|Parkinson’s disease & PD-related disorders 2016    

Generation of human authentic striatal neurons from pluripotent stem cells for transplantation in Huntington’s disease. Generazione di neuroni umani striatali autentici da cellule staminali pluripotenti per il trapianto nell’Huntington. Investments > €500k Italy Huntington’s disease 2016    

Utilization of human Parkinson’s disease specific neuroepithelial stem cells to define disease associated cellular phenotypes in a co-culture of oligodendrocytes and dopaminergic neurons – CORE Investments > €500k Luxembourg Parkinson’s disease & PD-related disorders 2016    

Modulation of tyrosine hydroxylase activity to control catecholamine synthesis and its effect on cellular metabolism – CORE Investments > €500k Luxembourg Parkinson’s disease & PD-related disorders 2016    

Comprehensive assessment of endophenotypes in neurodegenerative diseases – translating impaired molecular signalling pathways into novel therapeutic strategies for Parkinson’s disease – PEARL Investments > €500k Luxembourg Parkinson’s disease & PD-related disorders 2016    

Modelling idiopathic Parkinson’s disease-associated somatic variation in dopaminergic neurons – ATTRACT Investments > €500k Luxembourg Parkinson’s disease & PD-related disorders 2016    

The UPR in the cell-to-cell spreading of tau pathology in dementia. Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Identification of molecular and genetic mechanisms in familial Lewy Body Dementia: a novel approach Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

The disease process of hereditary frontotemporal dementia in the presymptomatic stage: a search for sensitive biomarkers Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Pathological substrate of clinical variability in AD Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Sphingolipids: a novel target in the treatment of Alzheimer Disease? Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Learning to resist Alzheimer’s disease: Novel molecular mechanisms that protect neurons against amyloid-beta Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

ABIDE: Alzheimer’s Biomarkers in Daily Practice Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

CAVIA: Cerebral Amyloid Angiopathy: Vascular Imaging and fluid markers of Amyloid deposition. Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

TAU IMAGING WITH [18F]T807 PET: THE NEW FRONTIER Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Exploring the potential of multi-target treatment for Alzheimer’s disease: towards an integrated and transdisciplinary approach Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Train the sedentary brain: move smart to reduce the risk of dementia Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Maintaining self-sufficiency, functional independence and social inclusion of community dwelling people with dementia and their informal caregivers Investments > €500k Netherlands Alzheimer’s disease & other dementias 2016    

Cognitive function, caregiver stress and cortisol: Mechanisms and implications for prevention of adverse health consequences in spouse dementia caregivers. Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Deep Phenotyping and Complex Genetics of ALS: A multidisciplinary population based approach Investments > €500k Ireland Motor neurone diseases 2016    

Living and dying with Amyotrophic Lateral Sclerosis: A Population based Analysis of Palliative Needs, Services and Outcomes in non-malignant terminal illness Investments > €500k Ireland Motor neurone diseases 2016    

National Centre for Social Research on Dementia (NCSRD) Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Dementia Friendly Irish Hospitals: Opportunities, Barriers, Costs and Solutions Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Towards resilience in family caregiving for people with dementia Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

BIOMARKAPD: Biomarkers for Alzheimer’s disease and Parkinson’s disease Investments > €500k|JPND Projects Ireland|JPND Alzheimer’s disease & other dementias 2016    

Modulating microglial function and its impact on neuronal function Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

The nuclear receptor TLX as a cell intrinsic regulator underlying inflammation and stress-induced changes in hippocampal neurogenesis: relevance to cognitive disorders Investments > €500k Ireland Neurodegenerative disease in general 2016    

Barriers of the CNS, tight junctions and novel therapeutic targets in neural disease. Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Project MinE Ireland: sequencing and analysis of 1,050 Irish genomes to identify the causes of amyotrophic lateral sclerosis Investments > €500k Ireland Motor neurone diseases 2016    

Cognitive Function, caregiver stress and cortisol: Mechanisms and implications for prevention of adverse health consequences in spouse dementia caregivers Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Evaluation Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Dementia Innovation Hub Investments > €500k Ireland Alzheimer’s disease & other dementias 2016    

Global Brain Health Initiative Investments > €500k Ireland Alzheimer’s disease & other dementias|Neurodegenerative disease in general 2016    

Global Brain Health Initiative – Partnerships Investments > €500k Ireland Neurodegenerative disease in general 2016    

New imaging techniques in the study of brain perfusion abnormalities and neuronal degeneration processes in people with multiple sclerosis and other degenerative neurological diseases. Associations between radiological markers and genetic polymorphisms of susceptibility and course of neurodegenerative diseases. Nuove tecniche…

Metal ions in disorders of aging: Interplay between Metallostasis and Proteostasis in Neurodegeneration. Ioni Metallici nelle Patologie da Invecchiamento: Interplay tra Metallostasi e Proteostasi nella Neurodegenerazione. Investments > €500k Italy Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders|Prion disease…

Design and synthesis of molecular probes to study the role of microglia in pathologies related to neuroinflammation. Progettazione e sintesi di sonde molecolari per lo studio del ruolo della microglia in patologie correlate alla neuroinfiammazione. Investments > €500k Italy Alzheimer’s…

Synaptic dysfunction in Alzheimer Disease: from new in vitro models to identification of new targets. Investments > €500k Italy Alzheimer’s disease & other dementias 2016    

Competence centers for deaf people in old age – Especially for people with dementia Investments > €500k Germany Alzheimer’s disease & other dementias 2016    

First-time biotechnological production and reconstitution of olive polyphenols and investigation of their potential for the prevention of neurodegenerative diseases Investments > €500k Germany Neurodegenerative disease in general 2016    

Competition “Local Alliances for People with Dementia” 2015 Investments > €500k Germany Alzheimer’s disease & other dementias 2016