Export as PDF
Cohort Acronym


Cohort type
General population-based cohort

Disease
Alzheimer's disease, Mild cognitive impairment (MCI)

Participant type
No diagnosis

Profile
Recruitment Period 2003-06 
Sample size at start or planned sample size if still recruiting 6734  
Estimated Current Sample Size 5,000 to 9,999 
Age at Recruitment 35-75   
Gender Male and Female 
Abstract

The major goals of this prospective cohort study of a randomly selected community sample are to: establish the prevalence and genetic, metabolic and environmental determinants of psychiatric disorders, cardiovascular risk factors (CVRF) and cardiovascular diseases (CVD) in the general population of the city of Lausanne; assess the mechanisms of the association between psychiatric disorders and CVRF / CVD.
Additional scientific questions focus on:

  • the identification of risk factors for the incidence and course of CVRF and psychiatric disorders;
    the identification of risk factors for cognitive impairment;
  • the testing of novel biological marker candidates and the incidence or course of CVRF/CVD or psychiatric disorders;
  • the testing of associations between brain anatomy patterns and CVRF and psychiatric disorders.

Last update: 19/12/2016

 
Country Switzerland 
Contact details
Institution name University Hospital Of Lausanne (CHUV) 
Website http://www.colaus.ch/ 
Principal Investiator (PI) Professor Martin Preisig (psychiatric part), Professor Gerard Waeber and Professor Peter Vollenweider (physical part) 
Contact email [email protected] 
Contact phone number +44 41213 147361 
Address CoLaus¦PsyCoLaus
CHUV
Rue du Bugnon 19
CH-1011 Lausanne 
Funders (Core support) GlaxoSmithKline (baseline investigation)
Swiss National Science Foundation (baseline and follow-up investigations) 

Variables Collected

Brain related measures: Behaviour, Cognitive function, Mental health, Neurological
Funtional rating: Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Respiratory
Biological samples: Blood, Urine
Genotyping: Gene screening
Brain imaging: Magnetic resonance imaging (MRI)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Income and finances, Informal support, Marital status
Health service utilisation: Formal health and social care service utilisation including private care
 
Export as PDF