VP-EDAD
Cohort type
Neurodegenerative disease-specific cohort
Disease
Alzheimer's disease, Dementia (unclassified), Mild cognitive impairment (MCI), Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
At-risk diagnosis
Profile
The Vallecas Project is developed in the Research Unit of the Alzheimer’s Center of the Reina Sofía Foundation by researchers of the CIEN Foundation. Its main objective is to determine a probabilistic algorithm for the identification of individuals at risk of dementia type Alzheimer’s disease (AD) in the course of a few years. This algorithm will be based on the combination of sociodemographic, clinical, neurological, neuropsychological, biological (from blood determinations) and neuroimaging (various 3 Tesla magnetic resonance modalities).
The recruitment phase of the Vallecas Project participants was extended from October 2011 to December 2013. Finally, a total of 1,213 volunteers aged between 70 and 85 and of both sexes were initially evaluated. Once included in the study, it is monitored annually for 5 years in order to assess the evolutionary profile of all participants, specifically identifying those who develop cognitive impairment and / or dementia. The cohort is being followed up annually for 4 years after the baseline.
C / Valderrebollo, 5
Centro Alzheimer Reina Sofía Foundation
Spain