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The major goals of this prospective cohort study of a randomly selected community sample are to: establish the prevalence and genetic, metabolic and environmental determinants of psychiatric disorders, cardiovascular risk factors (CVRF) and cardiovascular diseases (CVD) in the general population of the city of Lausanne; assess the mechanisms of the association between psychiatric disorders and CVRF / CVD.
Additional scientific questions focus on:
- the identification of risk factors for the incidence and course of CVRF and psychiatric disorders;
the identification of risk factors for cognitive impairment; - the testing of novel biological marker candidates and the incidence or course of CVRF/CVD or psychiatric disorders;
- the testing of associations between brain anatomy patterns and CVRF and psychiatric disorders.
Last update: 19/12/2016
Types General population-based cohort
Participant Types No diagnosis
Countries Switzerland
Genders Male and Female
Sample sizes 5,000 to 9,999
Ages 20 to 39|40 to 59|60 to 100
Brain related measures Behaviour|Cognitive function|Mental health|Neurological
Funtional rating Individual psychological
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Respiratory
Biological samples Blood|Urine
Genotyping Gene screening
Brain imaging Magnetic resonance imaging (MRI)
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Income and finances|Informal support|Marital status
Health service utilisation Formal health and social care service utilisation including private care
Institute names University Hospital Of Lausanne (CHUV)
Current Sample Sizes 5,000 to 9,999
age at recruitment 35-75
last updated
recruitment period 2003-06
estimated current sample size number value 4500
cohort acronym
start date 2003-06
pi Professor Martin Preisig (psychiatric part), Professor Gerard Waeber and Professor Peter Vollenweider (physical part)
website http://www.colaus.ch/
contact details CoLaus¦PsyCoLaus
CHUV
Rue du Bugnon 19
CH-1011 Lausanne
abstract PsyCoLaus is a prospective cohort study to assess the health and well-being of the city of Lausanne. 6,734 participants aged 35-75 were recruited between 2003 and 2006.
funders GlaxoSmithKline (baseline investigation)
Swiss National Science Foundation (baseline and follow-up investigations)
contact email [email protected]
contact phone number +44 41213 147361
estimated current sample size 5,000 to 9,999
sample sizes 6734
