{"id":5395,"date":"2015-12-15T16:46:00","date_gmt":"2015-12-15T16:46:00","guid":{"rendered":"http:\/\/www.neurodegenerationresearch.eu\/?p=5395"},"modified":"2015-12-15T16:46:38","modified_gmt":"2015-12-15T16:46:38","slug":"formation-of-new-blood-vessels-may-explain-parkinsons-symptoms","status":"publish","type":"post","link":"https:\/\/neurodegenerationresearch.eu\/es\/2015\/12\/formation-of-new-blood-vessels-may-explain-parkinsons-symptoms\/","title":{"rendered":"Formation of new blood vessels may explain Parkinson&#8217;s symptoms"},"content":{"rendered":"<p>The unwanted formation of blood vessels &#8212; angiogenesis &#8212; in the brain is likely to be the cause of intractable walking and balance difficulties for people who suffer from Parkinson&#8217;s disease, according to new research.<\/p>\n<p>Many people with Parkinson&#8217;s disease eventually experience walking and balance difficulties, despite adequate medication. Moreover, some patients cannot fully take dopamine-based medication, as dopamine can lead to side effects.<\/p>\n<p>The current research findings verify similar data from a previous study by other researchers, which was performed on brain tissue from a small number of deceased patients.<\/p>\n<p>\u00abThe strength of our study is the number of participants, and the fact that they are alive. Because many suffer from several parallel diseases at the final stage of their lives, it is difficult to analyse samples from deceased persons\u00bb, explains Oskar Hansson, reader at Lund University and consultant at Sk\u00e5ne University Hospital.<\/p>\n<p>The findings, published in the journal <em>Neurology<\/em>, were made when the researchers used a broad approach when looking for mechanisms to increase understanding of how Parkinson&#8217;s disease works. \u00abThe measurements showed clear connections between markers of angiogenesis in the brain and walking or balance difficulties among the participants. We also noted an increased permeability of the blood-brain barrier, which leads to blood components potentially leaking into the brain and causing damage\u00bb, says Oskar Hansson.<\/p>\n<p>Source: Lund University<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The unwanted formation of blood vessels &#8212; angiogenesis &#8212; in [&hellip;]<\/p>\n<a href=\"https:\/\/neurodegenerationresearch.eu\/es\/2015\/12\/formation-of-new-blood-vessels-may-explain-parkinsons-symptoms\/\">View Post<\/a>","protected":false},"author":3,"featured_media":4978,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[22],"tags":[295,88,106,180,77,115,156],"class_list":["post-5395","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-news","tag-angiogenesis","tag-brain","tag-brain-research","tag-neurodegeneration","tag-parkinsons","tag-parkinsons-disease-2","tag-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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