{"id":5132,"date":"2015-06-25T15:07:51","date_gmt":"2015-06-25T15:07:51","guid":{"rendered":"http:\/\/www.neurodegenerationresearch.eu\/?p=5132"},"modified":"2015-07-15T15:35:08","modified_gmt":"2015-07-15T15:35:08","slug":"how-huntingtons-disease-proteins-spread-from-cell-to-cell","status":"publish","type":"post","link":"https:\/\/neurodegenerationresearch.eu\/hu\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/","title":{"rendered":"How Huntington’s disease proteins spread from cell to cell"},"content":{"rendered":"

‘Seeding’ property provides new focus for treatment to delay progression of disorder<\/em><\/strong><\/p>\n

By identifying in spinal fluid how the characteristic mutant proteins of Huntington’s disease spread from cell to cell, researchers have created a new method to quickly and accurately track the presence and proliferation of these neuron-damaging compounds — a discovery that may accelerate the development of new drugs to treat this incurable disease.<\/p>\n

The researchers added that the cell-to-cell „seeding” property of these mutant proteins seems to be a critical part of the disease’s progression. Their findings also advance a new drug-discovery approach: stopping the cellular transfer of the seeding compounds. Study results appear online in the journal \u201cMolecular Psychiatry\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"

‘Seeding’ property provides new focus for treatment to delay progression […]<\/p>\nView Post<\/a>","protected":false},"author":3,"featured_media":4999,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[22],"tags":[128,94,247],"class_list":["post-5132","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-news","tag-drug-target","tag-huntingtons","tag-spinal-cells"],"acf":[],"yoast_head":"\nHow Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research\" \/>\n<meta property=\"og:description\" content=\"‘Seeding’ property provides new focus for treatment to delay progression […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/\" \/>\n<meta property=\"og:site_name\" content=\"JPND Neurodegenerative Disease Research\" \/>\n<meta property=\"article:published_time\" content=\"2015-06-25T15:07:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2015-07-15T15:35:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1754\" \/>\n\t<meta property=\"og:image:height\" content=\"1240\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"jpnd\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@JPNDeurope\" \/>\n<meta name=\"twitter:site\" content=\"@JPNDeurope\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"jpnd\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/\"},\"author\":{\"name\":\"jpnd\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#\\\/schema\\\/person\\\/a97e49cae588ead81db59e48a4e63c2a\"},\"headline\":\"How Huntington’s disease proteins spread from cell to cell\",\"datePublished\":\"2015-06-25T15:07:51+00:00\",\"dateModified\":\"2015-07-15T15:35:08+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/\"},\"wordCount\":121,\"publisher\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2015\\\/05\\\/Huntingtons.jpg\",\"keywords\":[\"Drug Target\",\"Huntington's\",\"spinal cells\"],\"articleSection\":[\"Research News (General)\"],\"inLanguage\":\"hu\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/\",\"url\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/\",\"name\":\"How Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2015\\\/05\\\/Huntingtons.jpg\",\"datePublished\":\"2015-06-25T15:07:51+00:00\",\"dateModified\":\"2015-07-15T15:35:08+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#primaryimage\",\"url\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2015\\\/05\\\/Huntingtons.jpg\",\"contentUrl\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2015\\\/05\\\/Huntingtons.jpg\",\"width\":1754,\"height\":1240},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/de\\\/2015\\\/06\\\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"How Huntington’s disease proteins spread from cell to cell\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#website\",\"url\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/\",\"name\":\"JPND Neurodegenerative Disease Research\",\"description\":\"Neurodegenerative Disease Research\",\"publisher\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"hu\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#organization\",\"name\":\"JPND\",\"url\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2022\\\/03\\\/logo.png\",\"contentUrl\":\"https:\\\/\\\/www.neurodegenerationresearch.eu\\\/wp-content\\\/uploads\\\/2022\\\/03\\\/logo.png\",\"width\":248,\"height\":129,\"caption\":\"JPND\"},\"image\":{\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/x.com\\\/JPNDeurope\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/#\\\/schema\\\/person\\\/a97e49cae588ead81db59e48a4e63c2a\",\"name\":\"jpnd\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g\",\"caption\":\"jpnd\"},\"url\":\"https:\\\/\\\/neurodegenerationresearch.eu\\\/hu\\\/author\\\/jpnd\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"How Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/","og_locale":"hu_HU","og_type":"article","og_title":"How Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research","og_description":"‘Seeding’ property provides new focus for treatment to delay progression […]","og_url":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/","og_site_name":"JPND Neurodegenerative Disease Research","article_published_time":"2015-06-25T15:07:51+00:00","article_modified_time":"2015-07-15T15:35:08+00:00","og_image":[{"width":1754,"height":1240,"url":"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg","type":"image\/jpeg"}],"author":"jpnd","twitter_card":"summary_large_image","twitter_creator":"@JPNDeurope","twitter_site":"@JPNDeurope","twitter_misc":{"Szerz\u0151:":"jpnd","Becs\u00fclt olvas\u00e1si id\u0151":"1 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#article","isPartOf":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/"},"author":{"name":"jpnd","@id":"https:\/\/neurodegenerationresearch.eu\/#\/schema\/person\/a97e49cae588ead81db59e48a4e63c2a"},"headline":"How Huntington’s disease proteins spread from cell to cell","datePublished":"2015-06-25T15:07:51+00:00","dateModified":"2015-07-15T15:35:08+00:00","mainEntityOfPage":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/"},"wordCount":121,"publisher":{"@id":"https:\/\/neurodegenerationresearch.eu\/#organization"},"image":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#primaryimage"},"thumbnailUrl":"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg","keywords":["Drug Target","Huntington's","spinal cells"],"articleSection":["Research News (General)"],"inLanguage":"hu"},{"@type":"WebPage","@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/","url":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/","name":"How Huntington's disease proteins spread from cell to cell - JPND Neurodegenerative Disease Research","isPartOf":{"@id":"https:\/\/neurodegenerationresearch.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#primaryimage"},"image":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#primaryimage"},"thumbnailUrl":"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg","datePublished":"2015-06-25T15:07:51+00:00","dateModified":"2015-07-15T15:35:08+00:00","breadcrumb":{"@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/"]}]},{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#primaryimage","url":"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg","contentUrl":"https:\/\/neurodegenerationresearch.eu\/wp-content\/uploads\/2015\/05\/Huntingtons.jpg","width":1754,"height":1240},{"@type":"BreadcrumbList","@id":"https:\/\/neurodegenerationresearch.eu\/de\/2015\/06\/how-huntingtons-disease-proteins-spread-from-cell-to-cell\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/neurodegenerationresearch.eu\/"},{"@type":"ListItem","position":2,"name":"How Huntington’s disease proteins spread from cell to cell"}]},{"@type":"WebSite","@id":"https:\/\/neurodegenerationresearch.eu\/#website","url":"https:\/\/neurodegenerationresearch.eu\/","name":"JPND Neurodegenerative Disease Research","description":"Neurodegenerative Disease Research","publisher":{"@id":"https:\/\/neurodegenerationresearch.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/neurodegenerationresearch.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"hu"},{"@type":"Organization","@id":"https:\/\/neurodegenerationresearch.eu\/#organization","name":"JPND","url":"https:\/\/neurodegenerationresearch.eu\/","logo":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/neurodegenerationresearch.eu\/#\/schema\/logo\/image\/","url":"https:\/\/www.neurodegenerationresearch.eu\/wp-content\/uploads\/2022\/03\/logo.png","contentUrl":"https:\/\/www.neurodegenerationresearch.eu\/wp-content\/uploads\/2022\/03\/logo.png","width":248,"height":129,"caption":"JPND"},"image":{"@id":"https:\/\/neurodegenerationresearch.eu\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/JPNDeurope"]},{"@type":"Person","@id":"https:\/\/neurodegenerationresearch.eu\/#\/schema\/person\/a97e49cae588ead81db59e48a4e63c2a","name":"jpnd","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/secure.gravatar.com\/avatar\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/b3244fc6099279fad29cb751cb709c5ee57befcda19ef0b44a4f0067989d7f7e?s=96&d=mm&r=g","caption":"jpnd"},"url":"https:\/\/neurodegenerationresearch.eu\/hu\/author\/jpnd\/"}]}},"_links":{"self":[{"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/posts\/5132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/comments?post=5132"}],"version-history":[{"count":0,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/posts\/5132\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/media\/4999"}],"wp:attachment":[{"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/media?parent=5132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/categories?post=5132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neurodegenerationresearch.eu\/hu\/wp-json\/wp\/v2\/tags?post=5132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}