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The longitudinal Study of Cognitive Change in Normal Healthy Old Age (LSCC) is a population study including 6,342 healthy residence of Greater Manchester and Newcastle-upon-Tyne aged from 42 to 92 in 1983. Two different batteries of cognitive tests were alternately administered biennially with additional questionnaires and Dna sample collection until 2003. The aims of the study were to:
to determine sources of variations in rates of cognitive change between individuals
to identify factors that slow or accelerate cognitive ageing and that prolong mental productivity or accelerate decline
to generate and test functional models for the processes of biological ageing, especially of ageing of the brain and the central nervous system
to test whether the neurophysiological and consequent cognitive changes differ in idiosyncratic patterns between individuals
Types General population-based cohort
Participant Types No diagnosis
Countries United Kingdom
Genders Male and Female
Sample sizes 5,000 to 9,999
Ages 40 to 59|60 to 100
Brain related measures
Funtional rating Individual physiological|Individual psychological
Anthropometric
Physical
Biological samples Blood|Saliva|Urine
Genotyping
Brain imaging Magnetic resonance imaging (MRI)
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Housing and accommodation|Informal support|Marital status|Occupation and employment
Health service utilisation
Institute names University of Manchester
Current Sample Sizes 5,000 to 9,999
age at recruitment 46-92
last updated
recruitment period 1983
estimated current sample size number value
cohort acronym LSCC
start date 1983
pi Patrick Rabbitt
website http://www.tandfonline.com/doi/abs/10.1080/13825580490511116
contact details University of Manchester
Age and Cognitive Performance Research Centre
Oxford Road
Manchester
M13 9PL
UK
abstract The longitudinal Study of Cognitive Change in Normal Healthy Old Age (LSCC) is a population study including 6,342 healthy residence of Greater Manchester and Newcastle-upon-Tyne aged from 42 to 92 in 1983.
funders U.K. Social Science Research Council (1983 to 1988), Medical Research Council (MRC), Economic and Social Research Council (ESRC)
contact email [email protected]
contact phone number
estimated current sample size
sample sizes 6,342