Cohort Acronym
GAP
Cohort type
Neurodegenerative disease-specific cohort
Disease
Alzheimer's disease, Frontotemporal dementia, Mild cognitive impairment (MCI), Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
At-risk diagnosis
Profile
GAP
Cohort type
Neurodegenerative disease-specific cohort
Disease
Alzheimer's disease, Frontotemporal dementia, Mild cognitive impairment (MCI), Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
At-risk diagnosis
Profile
Recruitment Period
May 11-Dec 12
Sample size at start or planned sample size if still recruiting
300
Estimated Current Sample Size
0 to 4,999
Age at Recruitment
40-80
Gender
Male and Female
Abstract
The Gipuzkoa Alzheimer Project (PGA) is a longitudinal study on pre-clinical Alzheimer’s disease. This study aims to investigate the prevalence, clinical, cognitive and neuroimaging features and potential risk factors related to cardiovascular health and lifestyles for pre-clinical AD in asymptomatic (or very mildly symtopmatic, e.g. SCD) subjects from the community.
Follow-up Scheduled every 3 years for a minimum of 12 years. The first 3-year follow-up was completed in June 2015. The loss of subjects in the follow up was 9 %. 80% of people who donated cerebrospinal fluid at the baseline visit did the same in this follow-up visit. Second follow-up visit (6 yrs) to be started in April 2017.
Last update: 16/01/2017
Country
Spain
Contact details
Institution name
Fundación CITA-Alzheimer Fundazioa
Principal Investiator (PI)
Dr. Pablo Martinez-Lage
Contact email
PI Email: [email protected]
Contact phone number
+34 (0) 943021792
Address
Fundación CITA-Alzheimer Fundazioa
Pº Mikeletegi 71
20009 Donostia-San Sebastián
España
Pº Mikeletegi 71
20009 Donostia-San Sebastián
España
Funders (Core support)
Fundacion Cita-Alzheimer Fundazioa
Basque Government
Gipuzkoa Local Government
Kutxa Fundazioa
Basque Government
Gipuzkoa Local Government
Kutxa Fundazioa
Variables Collected
Brain related measures: Mental health
Funtional rating: Individual physiological, Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular
Biological samples: Blood, Urine
Genotyping: N/A
Brain imaging: Magnetic resonance imaging (MRI), Magnetic resonance spectroscopy (MRS)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: N/A
Health service utilisation: N/A