Prospective Epidemiological Risk Factor Study

The Prospective Epidemiological Risk Factor (PERF) Study is an ambidirectional population-based study of postmenopausal women set up with the purpose of obtaining a better understanding of the aetiology and pathogenesis of age-related diseases. Participants were recruited from a source population of 8875 women residing in Denmark. The baseline examination (PERF I) comprised 5855 women with mean age of 70.8 years (49.7-88.8) and took place between 1999 and 2001. All subjects have been followed up with registry linkage using population-based national registries. Further, a subcohort was re-invited to attend a follow-up visit between 2013 and 2014 (PERF II). Registry data are available for all baseline participants. From the baseline population, 2103 were enrolled in PERF II.

Types General population-based cohort
Participant Types At-risk diagnosis
Countries Denmark
Genders Female
Sample sizes 0 to 4,999
Ages 40 to 59|60 to 100
Brain related measures
Funtional rating
Anthropometric Blood pressure|Height|Hip circumference|Waist circumference|Weight
Physical Cardiovascular|Musculoskeletal|Reproductive|Respiratory
Biological samples Blood|Urine
Genotyping Gene screening
Brain imaging
Brain banking
Lifestyle Alcohol|Dietary habits|Physical activity|Smoking
Socio-economic Education|Ethnic group|Family circumstances|Marital status|Occupation and employment
Health service utilisation Formal health and social care service utilisation including private care
Institute names Nordic Bioscience
Current Sample Sizes 0 to 4,999

age at recruitment 49-88
last updated
recruitment period 1999-2001; 2013-2014
estimated current sample size number value
cohort acronym PERF
start date 1999-2001; 2013-2014
pi Dr Cecilie Liv Bager and Morten Karsdal
website http://www.nordicbioscience.com/expertise/publications/cohort-profile-the-prospective-epidemiological-risk-factor-perf-study/
contact details Nordic Bioscience A/S,
Herlev Hovedgade 207,
DK-2730 Herlev,
Denmark
abstract  The Prospective Epidemiological Risk Factor (PERF) Study is an ambidirectional population-based study of postmenopausal women set up with the purpose of obtaining a better understanding of the aetiology and pathogenesis of age-related diseases.
funders  Danish Research Foundation
contact email [email protected]; PI Email: [email protected]
contact phone number 
estimated current sample size
sample sizes 2,103