Name of resource
A.I. Virtanen Institute/ Biocenter Kuopio, University of Eastern Finland
Name of Principal Investigator
| Title | Professor |
| First name | Jari |
| Last name | Koistinaho |
Address of institution where award is held
| Institution | A.I. Virtanen Institute, University of Eastern Finland |
| Street Address | Neulaniementie 2 |
| City | Kuopio |
| Postcode | 70211 |
Country
Finland
Website
http://www.uef.fi/aivi
Contact email
Summary
All models are available for academic research, most of them also for sponsored research
1a. The resource holds animal models relevant to the study of the following neurodegenerative diseases
Alzheimer’s disease and other dementias Motor neurone diseases Parkinson’s disease Huntington’s disease
1b. The resource holds:
Animals
2a. The resource acts as a centre for access and distribution to external groups (who are not the PIs of the resource)
2b. Procedures and rules for access
Apply to PI or co-ordinator at resource Access independent of collaboration with PI International access Access to industry
3a. Does the resource develop animal models for external groups
2
3b. Types of models provided
Wild type Genetically modified
4a This activity is supported as:
Independent of collaboration
4b. The supplied material deposited in a central repository
1
5a Disease models available
| Disease | Species | Available to external user (Y/N) | Full phenotypic character (Y/N or partial) | Phenotypes | Genotypes or other subtypes |
| AD | Mouse | Y | Partial | Tau aggregation, neuronal loss, learning deficits | |
| PD | C.elegans | Y | Partial | Degeneration of dopaminergic neurons, motor impairment | |
| ALS | Mouse | Y | Y | Motor impairment |
5b. Other models/phenotypes available through the resource relevant to neurodegenerative conditions
| No. of models | Available to external users | Full phenotypic characterisation available (Y/N or partial) | Nature of phenotype |
| 2 | Y | partial | AD tau pathology |
| 2 | Y | Y | Specific neurodegeneration, motor impairment |
7a. Maintenance of the resource is dependent on continued funding
2
7b. End date of current funding period
2012
7c. Expected lifespan of the resource (in years)
10