Prof. dr. W.M.H. van der Flier
VU University Medical Center
ABIDE: Alzheimers Biomarkers in Daily Practice
Alzheimer's disease & other dementias
The general aim of ABIDE is to enable the (cost)effective application of MRI, CSF, and PET diagnostic tests for Alzheimer’s Disease (AD) and its predecessor Mild Cognitive Impairment (MCI) in clinical practice (in secondary and tertiary care), taking into account patients perspective and wishes on their use. Such diagnostics should ultimately enhance the efficacy of treatment and contribute to lowering the socioeconomic burden of AD. The deliverables of ABIDE include new diagnostic guidelines, decision support algorithms, risk estimates, patient communication strategies and – tools and e-learning modules for healthcare specialists that collectively enable the wide-scale introduction of these new innovative diagnostics in clinical practice.
ABIDE will be executed by a strong public private project team of closely collaborating research organisations (VU Medical Center, Academic Medical Center, University Medical Center Utrecht), care institutions (a panel of 10 professionals working in local memory clinics, headed by Kennemer Gasthuis) knowledge institutes (Vilans), companies (Roche, Espria, Cyclotron, Piramal Imaging) and national and international advisors.
The project is structured into six work packages (WPs), of which the first three are aimed to develop diagnostic guidelines and decision support algorithms, whereas WP4 and 5 focus on patient communication and implementation of key deliverables. WP6 concerns project management.