Principal Investigators

    R?ži?ka Evžen Prof. MUDr. DrSc., FCMA


    General Faculty Hospital in Prague

    Contact information of lead PI


    Czech Republic

    Title of project or programme

    Analysis of bradykinesia and speech in Parkinson’s disease

    Source of funding information

    Ministry of Health of the Czech Republic

    Total sum awarded (Euro)

    € 150,000

    Start date of award


    Total duration of award in years



    Research Abstract

    Bradykinesia is the leading motor symptom of Parkinson’s disease (PD), and is crucial for diagnosis and for estimation of the patient’s functional deficit. Bradykinesia is generally described as reduction of amplitude, slowing down and irregularity of movements. In practice, bradykinesia is assessed using ordinal rating scales (most often, the UPDRS) that however hardly discriminate delicate differences in the severity of bradykinesia and its temporal changes. Therefore, BradykAn system has been developed for analysis of upper limb movements. The present project aims to validate the BradykAn system in comparison with other tests, and to verify its applicability in differential diagnosis of hypokinetic movement disorders and in monitoring of bradykinesia severity, including the effects of treatment. Another goal is to study the relationship between bradykinesia and hypokinetic dysartria, the characteristic speech problem in PD, as measured using advanced methods of acoustic analysis.

    Further information available at:

Types: Investments < €500k
Member States: Czech Republic
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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