Title of cohortCohort of Consultants from Health Examination Clinics
Name of Principal Investigator - Title
Name of Principal Investigator - First name
Name of Principal Investigator - Last name
Address of institution -Institution
Address of institution - Street address
Address of institution - City
Address of institution - Postcode
Funding sourceCNAMTS, DGS, Ministry of Health, Youth, Sport and Community Life in the Île-de-France region, IReSP, ANR, Public/private partnership through INSERM Transfer).
Q1a. Please indicate below if your cohort includes or expects to include, incidence of the following conditions?Neurodegenerative disease in general
Q1b. When are studies on the above condition(s) expected to become possible?
Q2a. In a single sentence what is the stated aim of the cohort?The objective is to establish a major epidemiological representative cohort of the general population and large workforce, in order to contribute to the development of epidemiological research and to provide information regarding public health.
Q2b. What distinguishes this cohort from other population cohorts?size, quality and diversity of data, monitoring methods
Q3a. i) Number of publications that involve use of your cohort to date
Q3a.ii) Please give up to three examples of studies to date (Principal Investigator, Institution, Title of Study)A. Elbaz, Inserm, Maladie de Parkinson : facteurs de risque et protecteurs| J-F. Dartigues, Inserm, Validation de cas de démence| S. Andrieu, Inserm, Big data et vieillissement
Q3b. If data on research outputs are already available please paste the publication list/other data or provide a link to where these data are publicly available
Q3c. If no research has been done as yet, please explain in a few sentences what information (i.e. research findings) you expect will be gained from the population
Q4a. Study criteria: what is the age range of participants at recruitment? Age in years From:
Q4a. Study criteria: what is the age range of participants at recruitment? To:
Q4b. Study criteria: what are the inclusion criteria?Adults between 18 and 69 years old and affiliated with the General Social Security Fund.
Q4c. Study criteria: what are the exclusion criteria?
Q5. What is the size of the cohort (i.e. how many participants have enrolled)?More than 15,000 participants
Q6a. Please describe what measures are used to characterise participantsSocioprofessionnal, lifestyle, environment, morbidity, health examination, cognitive tests
Q6b. Are there additional measures for participants with a clinical disorder?Medical records for some conditions
Q6c. Are there defined primary and secondary endpoints (e.g. defined health parameters)?
Q7. What is the study design (select all that apply)?Prospective cohort|Longitudinal
Q8. Are your cases matched byOther health assessment (not specified)
Q9a. Does your study include a specialised subset of control participants?
Q9b. If your study includes a specialised subset of control participants please describe
Q10a. i) Please enter the data collection start date
Q10a. ii) Please enter the data collection end dateContinuous; no end planned
Q10a. iii) Is data collection for this studyData collection ongoing| Data analysis ongoing
Q10b. If data collection is ongoing, are there plans to continue the cohort study beyond the current projected end date?Yes - intend to apply for funding
Q11. Is data collectedThrough links to other records or registers (e.g dental records, police records etc)
Other please specify hereQuestionnaires, health examination
Q12. Is there a system in place to enable re-contact with patients to ask about participation in future studies?Yes (participants given permission to be re-contacted via PIs)
Q13a. Please give information on the format and availability of data stored in a database (1)Data summarised in database
Q13a. Please give information on the format and availability of data stored in a database (2)
Q13a. Please give information on the format and availability of data stored in a database (3)
Q13a. Please give information on the format and availability of data stored in a database (4)
Q13b. Please give information on the format and availability of data held as individual records (1)
Q13b. Please give information on the format and availability of data held as individual records (2)
Q13b. Please give information on the format and availability of data held as individual records (3)Data held on computer based records
Q13b. Please give information on the format and availability of data held as individual records (4)
Please specify language used
Q14a. Is data available to other groups?
Q14b. If data is available to other groups what is the access policy/mechanisms for access?Apply to PI or co-ordinator at resource| National access| International access| Access to industry| Access restricted to peer-reviewed work| Applicant needs to provide separate external ethics approval | Resource has own ethics approval so usually no need for separate external ethics approval
Q15. What data sharing policy is specified as a condition of use?Data to be made publicly available immediately
Q16a. Are tissues/samples/DNA available to other groups?
Q16b i) If yes, please describe below:Living donors blood| Living donors: blood derivatives| Living donors: DNA
Q16b. ii) In what form are tissues/samples/DNA supplied?Primary Samples: Stabilised samples (frozen or fixed)
Q16b. iii) Is the access policy/mechanism for obtaining samples the same as that for obtaining data (Q14 above)?
Q17. Is information on biological characteristics available to other groups?
Types: Population Cohorts
Member States: France
Diseases: Neurodegenerative disease in general
Years: 2016
Database Categories: N/A
Database Tags: N/A
Export as PDF
