Principal Investigators


Evans, Alan C

Institution


McGill University

Contact information of lead PI


Country


Canada

Title of project or programme


Cortical connectivity in neurodevelopment and neurodegeneration

Source of funding information


CIHR

Total sum awarded (Euro)


€ 491,283

Start date of award


01/04/2013

Total duration of award in years


5

Keywords


Research Abstract


Different brain regions grow and degenerate in a coordinated pattern. We will map the differences in this pattern across individuals, across normal development, abnormal development and in neurodegenerative disease. Using large brain databases already in existence, we will relate these structural connectivity differences across individuals to differences in normal performance in memory, language and motor skills as they change over time and as they are degraded in Alzheimer’s Disease. Finally, we will use animal models of brain plasticity during learning to investigate the microstructural basis of structural connectivity observed with MR imaging in human brain.

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