Principal Investigators

    Solomon Alina

    Institution

    University of Eastern Finland

    Contact information of lead PI

    Country

    Finland

    Title of project or programme

    Fingerprinting the risk of dementia and likelihood of intervention response to facilitate prevention-related decision-making

    Source of funding information

    Academy of Finland

    Total sum awarded (Euro)

    € 326,481

    Start date of award

    01/09/2015

    Total duration of award in years

    3

    Keywords

    Research Abstract

    Dementia and Alzheimer disease prevention is a major public health priority. This project focuses on formulating tools for identifying high-risk individuals who may benefit from preventive interventions. Novel computer-based methods (Disease State Index, Disease State Fingerprint) will be used for analysis and visualization of a broad range of dementia-related factors and biomarkers. Specific aims include: 1) Risk index estimating an individual’s risk of cognitive impairment/dementia; 2) Intervention response index estimating an individual’s likelihood to respond to preventive interventions; 3) Planning a protocol for prevention-related decision-making. The project combines several large observational population-based studies (FINRISK, CAIDE, Vantaa 85+) and prevention trials (FINGER, MAPT, LipiDiDiet). It can produce comprehensive profiling tools that can facilitate personalization of preventive strategies in order to make them more effective.

    Further information available at:

Types: Investments < €500k
Member States: Finland
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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