Name of Fellow


Dr Sivaraman Purushothuman

Institution


Funder


NHMRC

Contact information of fellow


Country


Australia

Title of project/programme


Lewy bodies in patients with dementia – Determining common and unique mechanisms in relation to Alzheimer’s disease

Source of funding information


NHMRC

Total sum awarded (Euro)


€ 410,220

Start date of award


01/01/16

Total duration of award in years


4.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


dementia with lewy bodies | alzheimer disease | pathogenic mechanisms | ageing | dementia

Research Abstract


Alzheimer’s disease is the most common type of dementia but often has multiple mixed pathologies. For example, Alzheimer post mortem brains may have abnormal accumulation of Lewy bodies in certain parts of the brains, and could be diagnosed as Lewy body disease. This may represent a skewed representation of some dementia subtypes. This project will identify the biological determinants of dementia patients with Lewy body disease for better understanding and future therapeutic targeting.

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