Name of Fellow


Natunen Teemu

Institution


Funder


Academy of Finland

Contact information of fellow


Country


Finland

Title of project/programme


Molecular mechanisms of ADAMTSL3 and other brain-derived target genes in the cellular processes relevant for Alzheimer’s disease

Source of funding information


Academy of Finland

Total sum awarded (Euro)


€ 278,269

Start date of award


01/09/15

Total duration of award in years


3.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


Alzheimer's disease | amyloid precursor protein | APP | APP processing | amyloid-? | ADAMTSL3 | human brain samples

Research Abstract


Alzheimer’s disease (AD) is a progressive neurodegenerative disease and the most common cause of dementia. The aim of this project is to characterize the role of newly identified brain-derived factors in the pathogenic mechanisms of AD at the cellular level by utilizing cell-based models of AD and human AD brain samples. This project may lead to the identification of novel therapeutic targets and/or predictive biomarkers in AD.

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