Principal Investigators

    Soininen Hilkka


    University of Eastern Finland

    Contact information of lead PI



    Title of project or programme

    Multimodal analysis of Imaging and Biomarkers in Alzheimer’s disease

    Source of funding information

    Academy of Finland

    Total sum awarded (Euro)

    € 430,270

    Start date of award


    Total duration of award in years



    Research Abstract

    Dementia is a major health problem in the world. Alzheimer’s disease (AD) is the leading cause of dementia. Our aim is find biomarkers and biomarker combinations for early diagnosis and prediction of AD. A previous study, PredictAD, provided many tools for image analyses and a decision making tool “AD Disease State Fingerprint” to facilitate early diagnosis. Analysis of metabolomics and lipidomics from blood has potential for developing a blood based biomarker for early detection of AD. In this study we will validate PredictAD tools for neuroimage analysis, Disease State Finger Print, and blood markers detected in other cohorts. We will use data mining from patients cohorts including clinical, neuropsychological, MRI, genetic, and blood lipidomic, metabolomics, proteomic data to define the best possible predictive model of existing AD. We will also investigate the profile of selected risk genes and blood and CSF biomarkers on imaging findings.

    Further information available at:

Types: Investments < €500k
Member States: Finland
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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