Principal Investigators

    Dr Amy Wyatt


    University of Wollongong

    Contact information of lead PI



    Title of project or programme

    The effect of hypochlorite on the toxicity and clearance of the Alzheimer’s disease-associated amyloid beta peptide

    Source of funding information

    National Health and Medical Research Council

    Total sum awarded (Euro)

    € 309,202

    Start date of award


    Total duration of award in years



    Research Abstract

    Alzheimer’s disease (AD) is the leading cause of dementia worldwide and a growing burden on our aging society. Recent studies support the idea that in AD a deleterious relationship exists between inflammation in the brain and the accumulation of amyloid beta (Aß), a peptide with toxic properties. This proposal aims to examine the details of this relationship with a focus on the toxicity and clearance of Aß when it is modified by hypochlortie, a chemical that is generated during inflammation.

    Further information available at:

Types: Investments < €500k
Member States: Australia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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