The Cambridge City over-75s Cohort Study

The Cambridge City over-75s Cohort Study (CC75C) is a long-term follow-up study of a representative population-based sample of older people which started in 1985 from a survey of over 2,600 men and women aged 75 and above. Through a series of interviews and assessments spanning almost three decades they have contributed to one of the largest and longest-running longitudinal observational studies of ageing into older old age.
The initial study targeted all men and women aged 75 or older who were registered within a selection of geographically and socially representative general practices in Cambridge, and achieved a 95% response rate in six of the seven practices. From this original survey of 2610 people, 2166 individuals form the baseline sample for the longitudinal cohort. This group has been followed up through ten surveys, with sub-groups assessed more often. Similarly high response rates amongst participants still alive in their late 80s or 90s, and even amongst centenarians, have built an extensive resource of quantitative and qualitative data contributed by a representative sample of very old people and their relatives.
The focus in later years shifted to quality of life issues of ‘older old’ people near the end of life for which we have been interviewing relatives or carers of surviving members of the cohort all aged 95 or more, as well as these study participants themselves.

Last update: 05/01//2017

Types General population-based cohort
Participant Types No diagnosis
Countries United Kingdom
Genders Male and Female
Sample sizes 0 to 4,999
Ages 60 to 100
Brain related measures Behaviour|Cognitive function|Mental health|Neurological
Funtional rating Individual psychological
Anthropometric
Physical Hearing and Vision|Musculoskeletal
Biological samples Blood|Cerebral spinal fluid (CSF)|Other|Saliva
Genotyping Gene screening
Brain imaging
Brain banking Consent for brain donation
Lifestyle Alcohol|Physical activity|Smoking
Socio-economic Education|Family circumstances|Housing and accommodation|Informal support|Marital status|Occupation and employment|Unpaid care
Health service utilisation Formal health and social care service utilisation including private care
Institute names Cambridge Institute of Public Health
Current Sample Sizes 0 to 4,999

age at recruitment ≥75
last updated
recruitment period 1985-87
estimated current sample size number value 0
cohort acronym CC75C
start date 1985-87
pi Professor Carol Brayne
website http://www.cc75c.group.cam.ac.uk
contact details Department of Public Health and Primary Care, Cambridge Institute of Public Health, Forvie Site|University of Cambridge School of Clinical Medicine, Box 113 Cambridge Biomedical Campus, Cambridge CB2 0SR, UK
abstract  CC75 is a population study; its initial aim in 1985 was to look at ageing but has moved towards a study of people near the end of life (2016). 2,600 participants over 75 were recruitment.
funders  Most recent funders: BMA Foundation for Medical Research, Abbeyfield Research Foundation, National Institute for Health Research CLAHRC and The BUPA Foundation;
For full list of funders over three decades see: http://www.cc75c.group.cam.ac.uk/background/grants/
contact email PI Email: [email protected] Study Co-ordinator Email: [email protected] Computer Officer (Emily Zhao) Email: [email protected]
contact phone number +44 (0) 1223 330334
estimated current sample size 0 to 4,999
sample sizes 2166