STROKOG (The Stroke and Cognition Consortium)

STROKOG is a consortium of longitudinal studies of cognitive disorders following stroke, TIA or small vessel disease. Developed under the auspices of VASCOG (Society for the Study of Vascular Cognitive and Behavioural Disorders), it is the first international effort to harmonise work on post-stroke dementia and is being led by CHeBA researchers.

The consortium brings together studies that have examined post-stroke or other high vascular risk cohorts longitudinally, with cognitive decline and dementia (including sub-types) as primary outcome variables. The included studies (N=27; total sample of more than 10,000 individuals, representing 17 countries) have rich neuropsychological and MRI data, and some recent studies (n=3) have included amyloid imaging in sub-samples. A number of studies have CSF and/or plasma available for biomarker studies, and participant enrolment in brain banks for neuropathology.

Last Update 21/09/2017

Types General population-based cohort
Participant Types No diagnosis
Countries Australia|Finland|France|Germany|Hong Kong|Ireland|Netherlands|Nigeria|Poland|Singapore|South Africa|South Korea|Sweden|United Kingdom|USA
Genders Male and Female
Sample sizes 10,000 to 19,999
Ages 0 to 9|10 to 19
Brain related measures Behaviour|Cognitive function|Mental health|Neurological
Funtional rating Individual physiological|Individual psychological
Anthropometric Blood pressure|Height|Weight
Physical Cardiovascular
Biological samples Blood
Genotyping Gene screening
Brain imaging Magnetic resonance imaging (MRI)|Positron emission tomography (PET) – amyloid|Positron emission tomography (PET) fluorine18 flurodeoxyglucose (FDG)
Brain banking Consent for brain donation
Lifestyle Alcohol|Physical activity|Smoking
Socio-economic Education|Ethnic group|Marital status
Health service utilisation
Institute names Multiple
Current Sample Sizes 10,000 to 19,999

age at recruitment >12
last updated
recruitment period Ongoing
estimated current sample size number value 16000
cohort acronym STROKOG
start date Ongoing
pi Perminder Sachdev
website https://cheba.unsw.edu.au/group/strokog
contact details CHeBA (Centre for Healthy Brain Ageing)
UNSW Medicine
abstract  STROKOG is a consortium of longitudinal studies of cognitive disorders following stroke, TIA or small vessel disease.
funders  Vincent Fairfax Family Foundation
contact email Email: [email protected]
contact phone number 
estimated current sample size 10,000 to 19,999
sample sizes 12092