Triplication alpha-synuclein iPSCs (MRC Centre for Regenerative Medicine)

http://www.crm.ed.ac.uk/people/tilo-kunath
[email protected]

United Kingdom

Human induced pluripotent stem cells (iPSCs) were established from a family with triplication of the alpha-synuclein gene. A collection of lines were derived from a female Parkinson’s patient, AST, and also from her unaffected daughter, NAS. These lines were published in Devine et al, 2011 (PMID:21863007). A gene editted isogenic control line, AST23-2KO6, was created from a PD line, AST23. All the iPSC lines have been deposited into EBiSC (https://www.ebisc.org/) and are available for academic and industrial projects.
Parkinson’s disease & PD-related disorders
Induced Pluripotent Stem Cells (iPSC)
Yes
Access independent of collaboration with PI| International access| Access to industry
Yes

Patient derived| Gene edited

Yes

EBiSC, European Bank of induced Stem Cells
Yes

Indefinite
No

Experimental Models
United Kingdom

2016