The Swedish BioFINDER study

BioFINDER
The Swedish BioFINDER study

www.biofinder.se
[email protected]
ECR, SRC, Wallenberg etc
ECR, SRC, Wallenberg etc

Only through study

100% of baseline data, but longitudinal data is still colllected

Sweden

Yes
Access through collaboration with PI only| Local/ regional access| National access| International access| Access to industry| Access for pilot studies permitted
No requirement to make data publicly available
Yes
Living donors: blood| Living donors: DNA| Living donors: cerebro-spinal fluid
Secondary samples: plasma| Secondary samples: DNA
Yes
Yes, for all the cohort
To development of new biomarkers and brain imaging techniques for Dementia and Parkinsonian disorders with the aim to better understand the diease mechanisms, to improve early diagnosis and to advance drug development.

40
Oskar Hansson, Lund University, Increased amyloidogenic APP processing in APOE ?4-negative individuals with cerebral ?-amyloidosis| Oskar Hansson, Lund University, 18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology in MAPT mutation carriers| Oskar Hansson, Lund University, Comparison of Amyloid PET and CSF Biomarkers for Identifying Early Alzheimer’s Disease.
http://biofinder.se/publications/

1,000-5,000
1,001-5,000

Prospective cohort
Age| Sex
Yes
350 healthy elderly cases with cognitive testing, MRI, CSF biomarkers, blood biomarkers, Amyloid PET and some also Tau PET
Data collection ongoing| Data analysis ongoing| Closed to new patients
Yes – intend to apply for funding

Data summarised in database

No

Database on spreadsheet (e.g. excel)

No

No

No

The Swedish BioFINDER study
Alzheimer’s disease and other dementias| Parkinson’s disease

Case Control Studies
Sweden
Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders
2016