Dev

Repurposing Low-Cost Consumer Technology for Motion Correction in Dementia Neuroimaging Investments < €500k United Kingdom 2016    

Cardiff Fetal Tissue Bank: Quality assured tissue for biomedical research and clinical trial in neurodegenerative disease Investments < €500k United Kingdom 2016    

TgF344-AD (University College Cork) www.ucc.ie [email protected] Ireland TgF344-AD (University College Cork) Rat model of AD (TgF344-AD), which expresses the mutant human transgenes: amyloid precursor protein (APPsw) and presenilin 1 (PS1ΔE9). Alzheimer’s disease & other dementias Animals Yes Apply to PI…

Oxford Parkinson Disease Centre (University of Oxford) www.opdc.ox.ac.uk [email protected] United Kingdom Oxford Parkinson Disease Centre (University of Oxford) BAC trangsenic mouse and rat lines carrying wild-type or mutant variants of SNCA and LRRK2; human iPSC lines carrying mutations in SNCA,…

Microglia Cell Model (VU University Medical Center) www.vumc.com [email protected] The Netherlands Microglia Cell Model (VU University Medical Center) Microglia, isolated from post mortem human brain (obtained from the Netherlands Brain Bank) , are used to compare effects of Alzheimer’s, Parkinson’s…

TRE-11CGG-GFP (Erasmus MC) [email protected] The Netherlands TRE-11CGG-GFP (Erasmus MC) Doxycycline inducible mouse model expressing a Fmr1 control size of 11CGGs coupled to EGFP under control of a Tet-On promoter to study FXTAS; see Hukema et al. Cell Cycle 2014…

Triplication alpha-synuclein iPSCs (MRC Centre for Regenerative Medicine) [email protected] United Kingdom Triplication alpha-synuclein iPSCs (MRC Centre for Regenerative Medicine) Human induced pluripotent stem cells (iPSCs) were established from a family with triplication of the alpha-synuclein gene. A collection of…

G51D SNCA rat (MRC Centre for Regenerative Medicine) [email protected] United Kingdom G51D SNCA rat (MRC Centre for Regenerative Medicine) CRISPR/Cas9 technology was used by Dr Tomoji Mashimo (Kyoto Univeristy) to introduce a single amino acid mutation (Gly-51-Asp) into the…

Induced neuronal progenitor cells derived from patient fibroblasts (University of Sheffield) www.sitran.org [email protected] United Kingdom Induced neuronal progenitor cells derived from patient fibroblasts (University of Sheffield) The iNPC’s are generated to further support the ongoing research in Sheffield but are…

Batseson Centre – Zebrafish (University of Sheffield) www.sheffield.ac.uk/bateson