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“Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy” has been published in Stem Cell Reports. This work was supported in part by JPND through the CureALS project, selected in…
Physical aggression among people with dementia is not unusual. A new study shows that one-third of those diagnosed with Alzheimer’s disease or frontotemporal dementia were physically aggressive towards healthcare staff, other patients, relatives, animals and complete strangers. The study is…
“Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease” has been published in Nature. This work was supported in part by JPND through the InCure project, selected in the 2013 call for European research projects for Cross-Disease Analysis of Pathways related…
A research team has identified a new mechanism that causes the hallmark symptoms of Parkinson’s disease, namely tremors, rigidity, and loss of voluntary movement. The discovery presents a new perspective to three decades of conventional wisdom in Parkinson’s disease research.…
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Nearly a quarter century ago, a genetic variant known as ApoE4 was identified as a major risk factor for Alzheimer’s disease — one that increases a person’s chances of developing the neurodegenerative disease by up to 12 times. However, it…
“Hot-spot KIF5A mutations cause familial ALS” has been published in Brain. This work was supported in part by JPND through the STRENGTH project, selected in the 2012 risk factors call, and the PreFrontAls project, selected in the 2013 preventive strategies…
