Dev

It has long been understood that a protein called TDP-43 clumps together in brain cells of people with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease, and is associated with neuron death. This same protein is thought to…

In a new study, researchers have found the first evidence that the activation of a biological pathway called necroptosis causes cells to die. This neuronal loss is closely linked with Alzheimer’s severity, cognitive decline and extreme loss of tissue and…

A new discovery could help slow the progression of neurodegenerative diseases such as motor neuron disease (MND), dementia and neurological decline associated with ageing. Researchers have identified that tuning up the activity pathway of the DNA’s natural repair toolkit —…

The protein amyloid beta, which accumulates in clumps or plaques in the brains of people with Alzheimer’s disease, is the subject of new research that aims to disrupt the biochemical carving of its precursor protein before it reaches its final,…

Scientists have discovered a new method of observing the brain changes caused by Parkinson’s disease, which destroys motor neurons. Their research suggests that the damage could be tracked by observing fluid changes in a specific region of the brain. Using…

Researchers have revealed the molecular basis of the hereditary form of early-onset Alzheimer’s disease. These new findings offer compelling insights for the design of novel therapeutic strategies to tackle the disease. The hereditary form of Alzheimer’s disease is caused by…

Changes in the visual systems of newly diagnosed Parkinson’s disease patients may provide important biomarkers for the early detection and monitoring of the disease, according to a new study published online in the journal Radiology. Parkinson’s disease is a neurodegenerative…

Using DNA sequencing, researchers have examined bacteria in post-mortem brains from patients with Alzheimer’s disease. Their findings indicate increased bacterial populations and different proportions of specific bacteria in Alzheimer’s, compared with healthy brains. These findings may support evidence that bacterial…