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Dev

Joined: October 9, 2025
Articles: 6278

Research News (General)

Making brain implants smaller could prolong their lifespan

Many diseases, including Parkinson’s disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring, which diminishes their effectiveness and can necessitate additional surgeries to replace them. Now, in a study…

Dev
July 26, 2017

JPND Publications

α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading

“α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading” has been published in Acta Neuropathologica. This work was supported in part by JPND through the NeuTARGETS project, selected in the 2013…

Dev
July 25, 2017

Research News (General)

Spread of tau protein measured in brains of Alzheimer’s patients

In a new study published in Molecular Psychiatry, researchers have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer’s disease. Their results show that the size of the deposit and the speed…

Dev
July 25, 2017

JPND Publications

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions

“KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions” has been published in Cell Reports. This work was supported in part by JPND through the RiMod-FTD project, selected in the 2012 Risk Factors call.

Dev
July 24, 2017

Research News (General)

What is survival among patients with Parkinson’s, Dementia with Lewy bodies?

A new article published in JAMA Neurology compares survival rates among patients with synucleinopathies, including Parkinson’s disease, dementia with Lewy bodies, Parkinson’s disease dementia and multiple system atrophy with parkinsonism, with individuals in the general population. The population-based study included…

Dev
July 24, 2017

cohorts

Prospective study of individuals at risk for spinocerebellar ataxia type 1, type 2, type 3 and type 6 (SCA1, SCA2, SCA3, SCA6)

The aim of RISCA is to answer the following questions: What is the incidence of disease manifestation in mutation carriers? Which clinical signs precede the onset of manifest ataxia in SCA1, SCA2, SCA3 and SCA6? What are the prevalence and…

Dev
July 21, 2017

40 to 59, 500,000+, 60 to 100, Alcohol, Blood, Blood pressure, Cancer Epidemiology Unit, Oxford, Cardiovascular, Dietary habits, Education, Ethnic group, Family circumstances, Female, Formal health and social care service utilisation including private care, Gene screening, General population-based cohort, Hearing and Vision, Height, Hip circumference, Housing and accommodation, Informal support, Marital status, Musculoskeletal, No diagnosis, Occupation and employment, Physical activity, Reproductive, Respiratory, Smoking, United Kingdom, Unpaid care, Waist circumference, Weight

Million Women Study

The Million Women Study is the largest study of women’s health in the world. In 1996-2001, a quarter of UK women then aged 50-64 years (1.3 million women) joined the study. The aim of the study is to provide reliable…

Dev
July 21, 2017

cohorts

The Gazel Cohort

The original GAZEL cohort was composed of 20,625 employees of the French national gas and electricity companies (15,011 male employees then aged 40 to 50 years and 5,614 women between 35 and 50 years old) at its inception in 1989.…

Dev
July 21, 2017

cohorts

The EUROSCA Natural History Study

The key goal of EUROSCA-NHS is to determine and compare the rate of disease progression in SCA1, SCA2, SCA3 and SCA6. To this end, a newly developed and validated ataxia scale (Scale for the Assessment and Rating of Ataxia, SARA)…

Dev
July 21, 2017

cohorts

Constances Cohort

The CONSTANCES general-purpose cohort is intended to serve as an epidemiological research infrastructure accessible to the epidemiologic research community with a focus on chronic diseases and aging. CONSTANCES is designed as a randomly selected representative sample of French adults aged…

Dev
July 21, 2017

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