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Dev

Joined: October 9, 2025
Articles: 6278

JPND Publications

Assessment of the factorial validity and reliability of the ALSFRS-R: a revision of its measurement model

“Assessment of the factorial validity and reliability of the ALSFRS-R: a revision of its measurement model” has been published in Journal of Neurology. This work has been supported in part by JPND through the SOPHIA project, selected in the 2011 Biomarkers…

Dev
June 19, 2017

Research News (General)

On the trail of Parkinson’s disease

Researchers have succeeded in analysing the effects of selective mutations of the alpha-synuclein protein, a protein that is closely linked to Parkinson’s disease. Examining the effects of changing a single amino acid in the protein, the physicochemists were able to…

Dev
June 19, 2017

JPND Publications

Virtual brain biopsies in ALS: Diagnostic classification based on in vivo pathological patterns

“Virtual brain biopsies in amyotrophic lateral sclerosis: Diagnostic classification based on in vivo pathological patterns” has been published in the journal Neurolmage: Clinical. This work was supported in part by JPND through the SOPHIA project, selected in the 2011 Biomarkers…

Dev
June 16, 2017

Research News (General)

Common factor links neurodegenerative disease in young and old

Scientists have identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly: frontotemporal dementia (FTD) and neuronal ceroid lipofuscinosis (NCL). This study was published in the journal Science Translational Medicine. FTD is one of…

Dev
June 16, 2017

JPND Publications

Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells

“Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells” has been published in the journal Nucleic Acids Research. This work was supported in part by JPND through the RiMod-FTD project, selected in the 2012…

Dev
June 15, 2017

Research News (General)

Inflammatory pathways link to obsessive behaviors in a common form of dementia

Scientists have identified that mutations in a protein commonly linked to frontotemporal dementia (FTD) result in obsessive-like behaviors. They linked these behaviors to immune pathways, implicating that targeting key components of the immune system could be a new therapeutic strategy…

Dev
June 15, 2017

JPND Publications

A protocol for manual segmentation of medial temporal lobe subregions in 7 tesla MRI

“A protocol for manual segmentation of medial temporal lobe subregions in 7 tesla MRI” has been published in the journal NeuroImage: Clinical. This work was supported in part by JPND through the EUFIND project, selected in the 2016 Brain Imaging Working…

Dev
June 13, 2017

Research News (General)

Prolonged Sleep May Predict Dementia Risk

Data from the Framingham Heart Study has shown that people who consistently sleep more than nine hours each night had double the risk of developing dementia in 10 years as compared to participants who slept for 9 hours or less.…

Dev
June 12, 2017

JPND Publications

Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease

“Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease: a clinical interpretation strategy” has been published in the European Journal of Human Genetics. This work was supported in part by JNPD through the PERADES project, selected in the…

Dev
June 9, 2017

Research News (General)

Cracking the code of Huntington’s disease

Huntington’s disease is caused by a gene mutation that causes an abnormal form of the protein huntingtin to build up in the brain. Small chemical modifications on different parts of huntingtin could reduce its toxicity and aggregation, but as many…

Dev
June 8, 2017

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