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Sphingolipids and Inflammation in the Development and Progression of Alzheimers Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 3) Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Diabetes Status and Brain Amyloid in Middle Aged Hispanics Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Peripheral and brain levels of advanced glycation end products AGEs and incident Alzheimers disease and neuropathology Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Nonlinear Models of Cognition Preceding AD and non-AD in a Biracial Population Sample Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Changes in arterial stiffness, cognition and dementia risk in a diverse cohort Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Cell autonomous and non-cell autonomous roles of the GWAS risk factor BIN1 in Alzheimers disease neuropathology Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Involvement of myelin integrity in Alzheimers disease pathogenesis Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Solid State NMR Structural Analysis of Oligomeric Alzheimers Beta-Amyloid Peptide Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Targeting the hematopoietic system: the role of hematopoietic growth factors in restricting A-beta accumulation in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Molecular Mechanisms Underlying Mitochondrial Dynamics Abnormalities in Alzheimer Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

CELL AND MOLECULAR PATHOBIOLGY OF ALZHEIMERS DISEASE Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Tyrosine phosphorylation in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

White matter damage in age-related cognitive decline Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Trafficking and Endosomal Sorting of APP and BACE-1 Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Immune regulated amino acid pathways in Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Mild Cognitive Impairment: a Prospective Community Study Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Lifecourse health, cerebral pathology and ethnic disparities in dementia Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Epidemiologic Study of Neural Reserve and Neurobiology of Aging Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

The NIA Genetics of Alzheimers Disease Data Storage Site Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Longitudinal interactive vascular exposure and Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Epidemiology of Familial Late-Onset Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Epidemiologic Study of TDP-43 Pathology in Aging and Dementia Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

MRI, Cognitive, Genetic and Biomarker Precursors of AD & Dementia in Young Adults Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Plasma Amylin Impact on Cognitive Function and Brain Morphology in the Framingham Heart Study Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Preclinical AD: Correlates of Amyloid, Tau PET and fcMRI in Framingham Gen 3 Young Adults Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Role of microRNA-33 in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Role of LDLR in regulating metabolism of Apolipoprotein E and Amyloid-beta Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Physiology and Pathophysiology of Apolipoprotein E receptor-2 splicing in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Molecular Regulation of AEP during Ageing Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Pathogenic role for formin mediated microtubule stabilization pathways in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

microRNA (miRNA) signaling in Alzheimers disease(AD) Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Membrane interaction and disruption by the Alzheimers amyloid-beta peptide Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Molecular mechanisms and cellular implications of tau dysfunction Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Tau-Spliceosome Interactions in Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

A multi-scale data-driven model of the Abeta pore function and Ca2+ toxicity in Alzheimers disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Mechanisms of Apolipoprotein E Isoform Conferred Susceptibility and Resistance to Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Role of Systemic Amylin Dyshomeostasis in Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Regulation of tau expression in Alzheimer disease and aging Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Understanding the mechanism of SPl1 dependent Alzheimer disease risk Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Cell type specific epigenetic analysis to understand complex mechanisms underlying Alzheimers disease phenotypes Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Structure and Inhibition of Amyloid in Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Formation and Propagation of Tau Oligomeric Strains in Alzheimers Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Contribution of DNA Repair Deficits to Alzheimer Pathogenesis Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Exosome-mediated propagation of pathogenic tau protein Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Characterizing and Targeting Pyk2 Kinase in Alzheimer’s Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

The Role of KCa3.1 in Neuroinflammation in Alzheimer Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

ApoE isoform-specific therapy for Alzheimer disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016    

Linking Tau Structure to Its Functions and Mechanisms in Alzheimer’s Disease Investments > €500k United States of America Alzheimer’s disease & other dementias 2016