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SAMS – Software Architecture for Mental health Self management

SAMS – Software Architecture for Mental health Self management Investments < €500k United Kingdom 2016

Metal-ion-based neurodegeneration: enabling techniques for understanding, detection, and treatment

Metal-ion-based neurodegeneration: enabling techniques for understanding, detection, and treatment Investments < €500k United Kingdom 2016

100 kHz magic angle spinning for development of solid-state NMR methodology for probing protein dynamics

100 kHz magic angle spinning for development of solid-state NMR methodology for probing protein dynamics Investments < €500k United Kingdom 2016

Whole genome sequencing in patients and families with dementia: building an open access UK resource

Whole genome sequencing in patients and families with dementia: building an open access UK resource Investments < €500k United Kingdom 2016

Disentangling the genetic, pathophysiological and classification complexities of vascular dementia

Disentangling the genetic, pathophysiological and classification complexities of vascular dementia Investments < €500k United Kingdom 2016

Effect of GLP1 analogue, Liraglutide on cerebral glucose metabolism and microglial activation in Alzheimer’s disease

Effect of GLP1 analogue, Liraglutide on cerebral glucose metabolism and microglial activation in Alzheimer’s disease Investments < €500k United Kingdom 2016

PREVENT Research Programme

PREVENT Research Programme Investments < €500k United Kingdom 2016

Mechanisms underlying the tau protein-mediated effects of amyloid beta on synaptic plasticity

Mechanisms underlying the tau protein-mediated effects of amyloid beta on synaptic plasticity Investments < €500k United Kingdom 2016

Disentangling network dysfunction in Alzheimer’s disease pathology: cause, consequence and rescue

Disentangling network dysfunction in Alzheimer’s disease pathology: cause, consequence and rescue Investments < €500k United Kingdom 2016

Dissecting the cellular mechanisms driving disease progression in CHMP2B activated Frontotemporal Dementia: Identifying Innate immune activation and the co-regulation of membrane traffic in neurons

Dissecting the cellular mechanisms driving disease progression in CHMP2B activated Frontotemporal Dementia: Identifying Innate immune activation and the co-regulation of membrane traffic in neurons Investments < €500k United Kingdom 2016

The influence of cortical neurodegenerative pathology on white matter integrity

The influence of cortical neurodegenerative pathology on white matter integrity Investments < €500k United Kingdom 2016

Hydrogen sulphide-mediated sulfhydration of the K+ channel Kv2.1: A new signalling pathway to target in the treatment of Alzheimer’s disease.

Hydrogen sulphide-mediated sulfhydration of the K+ channel Kv2.1: A new signalling pathway to target in the treatment of Alzheimer’s disease. Investments < €500k United Kingdom 2016

Zinc deficiency drives inflammation-dependent cognitive decline in Alzheimer’s disease

Zinc deficiency drives inflammation-dependent cognitive decline in Alzheimer’s disease Investments < €500k United Kingdom 2016

Diabetes, Defective Nutrient Signalling and Dementia: an Epidemiological Neuropathology Approach

Diabetes, Defective Nutrient Signalling and Dementia: an Epidemiological Neuropathology Approach Investments < €500k United Kingdom 2016

The dynamic role of astrocyte secreted APOε4 in Alzheimer’s disease: investigations using human induced pluripotent stem cells

The dynamic role of astrocyte secreted APOε4 in Alzheimer’s disease: investigations using human induced pluripotent stem cells Investments < €500k United Kingdom 2016

Detecting early dementia in mice: The contribution of amyloid vs tau

Detecting early dementia in mice: The contribution of amyloid vs tau Investments < €500k United Kingdom 2016

“Am I the right way up?” Investigating balance problems in posterior cortical atrophy

“Am I the right way up?” Investigating balance problems in posterior cortical atrophy Investments < €500k United Kingdom 2016

The contribution of epigenetic phenomena to Alzheimer’s disease: an integrated genetic-epigenetic analysis

The contribution of epigenetic phenomena to Alzheimer’s disease: an integrated genetic-epigenetic analysis Investments < €500k United Kingdom 2016

Preventing cognitive decline and dementia from cerebral microvascular disease

Preventing cognitive decline and dementia from cerebral microvascular disease Investments < €500k United Kingdom 2016

Role of TMEM106B in C9ORF72-related Frontotemporal Lobar Degeneration

Role of TMEM106B in C9ORF72-related Frontotemporal Lobar Degeneration Investments < €500k United Kingdom 2016

Synthetic Heparins as Safe Disease-modifying Drugs for Early-Stage Treatment of AD via Inhibition of Beta-Secretase: Evaluation in a Transgenic Mouse Model

Synthetic Heparins as Safe Disease-modifying Drugs for Early-Stage Treatment of AD via Inhibition of Beta-Secretase: Evaluation in a Transgenic Mouse Model Investments < €500k United Kingdom 2016

Intelligence led drug discovery for the amyloid cascade

Intelligence led drug discovery for the amyloid cascade Investments < €500k United Kingdom 2016

Can brain training lead to short term and sustained improvements in cognitive function?

Can brain training lead to short term and sustained improvements in cognitive function? Investments < €500k United Kingdom 2016

Title: Alpha-Synuclein and Cellular Iron Reduction

Title: Alpha-Synuclein and Cellular Iron Reduction Investments < €500k United Kingdom 2016

Double-blind randomised crossover placebo-controlled pilot trial with intra-nasal Oxytocin to increase social cognitive function and reduce carer burden in frontotemporal dementia.

Double-blind randomised crossover placebo-controlled pilot trial with intra-nasal Oxytocin to increase social cognitive function and reduce carer burden in frontotemporal dementia. Investments < €500k United Kingdom 2016

Phenotyping the immune response in Alzheimer’s disease by flow cytometry

Phenotyping the immune response in Alzheimer’s disease by flow cytometry Investments < €500k United Kingdom 2016

Alzheimer’s Research UK Bristol and Bath Network Centre Grant

Alzheimer’s Research UK Bristol and Bath Network Centre Grant Investments < €500k United Kingdom 2016

Alzheimer’s Research UK South Coast Network Centre Grant

Alzheimer’s Research UK South Coast Network Centre Grant Investments < €500k United Kingdom 2016

Phosphorylation of kinesin light chain and calsyntenin-1/alcadein mediated axonal transport and processing of APP in Alzheimer’s disease

Phosphorylation of kinesin light chain and calsyntenin-1/alcadein mediated axonal transport and processing of APP in Alzheimer’s disease Investments < €500k United Kingdom 2016

Cortico-striatal contributions to symptomology in dementia: new targets for therapy

Cortico-striatal contributions to symptomology in dementia: new targets for therapy Investments < €500k United Kingdom 2016

Alzheimer’s Research UK Newcastle Network Centre Grant

Alzheimer’s Research UK Newcastle Network Centre Grant Investments < €500k United Kingdom 2016

Alzheimer’s Research UK Midlands Network Centre Grant – Year 2

Alzheimer’s Research UK Midlands Network Centre Grant – Year 2 Investments < €500k United Kingdom 2016

Next Generation Sequencing of Alzheimer’s Disease (AD) Genes in non-familial early-onset AD (EOAD).

Next Generation Sequencing of Alzheimer’s Disease (AD) Genes in non-familial early-onset AD (EOAD). Investments < €500k United Kingdom 2016

The use of a histology slide scanner to aid in the understanding of disease progression and mechanisms in dementia

The use of a histology slide scanner to aid in the understanding of disease progression and mechanisms in dementia Investments < €500k United Kingdom 2016

Online Cognitive Behavioural Therapy (CBT) trial – statistics

Online Cognitive Behavioural Therapy (CBT) trial – statistics Investments < €500k United Kingdom 2016

Mnemic neglect in people affected with Mild Alzheimer’s disease: replicating and extending findings from Experimental Social Psychology

Mnemic neglect in people affected with Mild Alzheimer’s disease: replicating and extending findings from Experimental Social Psychology Investments < €500k United Kingdom 2016

The Perceptions and Experiences of Children and Young People with a Parent with Dementia

The Perceptions and Experiences of Children and Young People with a Parent with Dementia Investments < €500k United Kingdom 2016

After the Liverpool Care Pathway – What next for people with dementia?

After the Liverpool Care Pathway – What next for people with dementia? Investments < €500k United Kingdom 2016

Biodistribution, pharmacokinetic and toxicity studies on a novel retro-inverso peptide inhibitor of beta-amyloid oligomer formation

Biodistribution, pharmacokinetic and toxicity studies on a novel retro-inverso peptide inhibitor of beta-amyloid oligomer formation Investments < €500k United Kingdom 2016