Cohort – KNDD-LANDSCAPE

Title of the cohort
Cohort – KNDD-LANDSCAPE
Acronym for cohort
LANDSCAPE
Name of Principal Investigator

Title	Prof. Dr.
First name	Richard
Last name	Dodel

Address of institution where award is held

Institution	Dept. of Neurology, University Marburg
Street Address	Rudolf-Bultmann-Str. 8
City	Marburg
Postcode	35039

Country
Germany
Website
http://www.therapieforschung-neurologie.eu
Contact email
[email protected]
Funding source

1. The cohort includes, or expects to include, incidence of the following conditions

• Alzheimer’s disease and other dementias
• Parkinson’s disease

When studies on the above condition(s) are expected to become possible
2011 – 2015
2a. Stated aim of the cohort
To investigate the development of and risk factors of dementia in patients with Parkinson’s disease and Lewy body dementia
2b. Features distinguishing this cohort from other population cohorts

3a. i) Number of publications that involve use of cohort to date
0
3a. ii) Up to three examples of studies to date (PI, Institution, Title of Study)

3b. Publication list/link to where data or publications are accessible (if available)

3c. Information (i.e. research findings) expected to be gained from the population cohort

4a. Study criteria: age range of participants at recruitment

Age in years from:	45
To (‘until death’ if applicable):	80

4b. Study criteria: inclusion criteria
Parkinson’s disease; Parkinson’s disease and dementia; Parkinson’s disease with MCI; Lewy body dementia
4c. Study criteria: exclusion criteria
Other dementias
5. Size of the cohort (i.e. number of participants enrolled)
1,000 – 5,000 participants
6a. Measures used to characterise participants
Detailed neuropsychometric testing; UPDRS; clinical examination; cMRI
6b. Additional measures for participants with a clinical disorder

6c. Are there defined primary and secondary endpoints (e.g. defined health parameters)
No
7. Study design

• Prospective cohort
• Longitudinal

8. Cases matched by

• Age
• Cognitive function
• Physical ability

9a. Does the study include a specialised subset of control participants
Yes
9b. If yes, description of specialised subset of control participants

10a. i) Data collection start date
01-01-2010
10a. ii) Data collection end date

10a iii) Data collection for this study is

• Data collection ongoing
• Data analysis ongoing

10b. Plans to continue the cohort study beyond the current projected end date

11. Data collected

12. System in place to enable re-contact with patients for future studies

13a. Format and availability of data stored in a database

Language used:

13b. Format and availability of data held as individual records

Language used:

14a. Are data available to other groups
Yes
14b. Access policy/mechanisms for access if data are available to other groups

15. Data sharing policy specified as a condition of use
Data to be made publicly available immediately
16a. Are tissues/samples/DNA available to other groups
Yes
16b. i) Description of available tissues/samples/DNA

16b. ii) Form available tissues/samples/DNA are supplied in

16b. iii) Is the access policy/mechanism for obtaining samples the same as that for obtaining data

17. Is information on biological characteristics available to other groups

• Yes, for all the cohort

Cohort – KNDD-LANDSCAPE

Population Cohorts
Germany
Alzheimer’s disease & other dementias|Parkinson’s disease & PD-related disorders