Export as PDF
Cohort Acronym

Cohort type
General population-based cohort

Alzheimer's disease, Dementia (unclassified), Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia

Participant type
No diagnosis

Recruitment Period 1978-80 
Sample size at start or planned sample size if still recruiting 7735  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment 40-59   
Gender Male 

The British Regional Heart Study (BRHS) is a prospective study in middle-aged men drawn from general practices in 24 British towns, 7,735 men were recruited in 1978-1980. It was set up to determine the factors responsible for the considerable variation in coronary heart disease, hypertension and stroke in Great Britain. It also seeks to determine the causes of these conditions in order to provide a rational basis for recommendations towards their prevention.

Following the collection of baseline date in 1978-80 the cohort has been followed up through the participants, two-yearly GP Record Reviews, and the Office of Population and Census Surveys. Participants have been re-contacted through questionnaires or assessment in 1983-85, 1992, 1996, 1998-2000, 2003, 2005, 2007 and 2010-2012, 2014, 2015, 2016.

Last update – 21/02/2017

Country United Kingdom 
Contact details
Institution name University College, London 
Principal Investiator (PI) Professor Peter Whincup and Professor Goya Wannamethee 
Contact email [email protected] 
Contact phone number +44 (0) 207 830 2335 U20 
Address British Regional Heart Study (BRHS)
Department of Primary Care & Population Health
Institute of Epidemiology and Health Care
UCL Faculty of Population Health Sciences
UCL Medical School
Royal Free Campus
Rowland Hill Street,
London NW3 2PF UK 
Funders (Core support) British Heart Foundation 

Variables Collected

Brain related measures: Cognitive function, Mental health, Neurological
Funtional rating: Individual physiological, Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Musculoskeletal, Respiratory
Biological samples: Blood, Urine
Genotyping: N/A
Brain imaging: N/A
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Housing and accommodation, Income and finances, Informal support, Marital status, Occupation and employment
Health service utilisation: N/A
Export as PDF